IDH1R132C_U251_ER_Untreated_vs_IDH1WT_U251_ER_Untreated

Profile details

Identifier: MTBLS1974_0001_00000002
Linked study: MTBLS1974 — IDH1 Mutations Induce Organelle Defects Via Dysregulated Phospholipids (CSHpos)
Comparison: IDH1R132C_U251_ER_Untreated vs IDH1WT_U251_ER_Untreated
Group A: IDH1R132C mutation in U251 cells, untreated, Endoplasmic Reticulum. Helps in understanding the mutation effect on ER morphology without treatment
Group B: IDH1 Wild type in U251 cells, untreated, Endoplasmic Reticulum. Provides baseline for comparison with mutated samples
Total features tested: 28
Significant features: 8
p-value threshold: 0.05
Ratio threshold (upper): 1.5
Ratio threshold (lower): 1/1.5
Date created: 2025-09-26 00:00:00

Metabolite ID (InChI Key)	Name	Direction	Ratio	p-value
LAXQYRRMGGEGOH-JXRLJXCWSA-N	PC(20:4(5<i>Z</i>,8<i>Z</i>,11<i>Z</i>,14<i>Z</i>)/0:0)	down	0.4912	0.000706
QCEZSXZDLSGARX-JTDYEGOHSA-N	—	down	0.481	0.00128
ZOJBSSVHFSBHMP-JJJSWPRASA-N	LysoPC(22:4)	down	0.5652	0.00198
LQQRQYIGEYFSIG-UWESVXFQSA-N	PC(18:3(6Z,9Z,12Z)/24:1(15Z))	down	0.4894	0.0077
HEQMDGOBDIGJOC-XMMPIXPASA-N	lyso-PE(20:0/0:0)	up	1.559	0.00123
AXZGUCXCTZMPTR-UVGACIQRSA-N	PC(18:0/22:4(7Z,10Z,13Z,16Z))	down	0.6179	0.00535
ALJUYAAJNSNTHU-PVPDQLFYSA-N	—	down	0.6484	0.00459
XLKQWAMTMYIQMG-SVUPRYTISA-N	—	down	0.6081	0.00998