{"@type":"Dataset","go_id":["https://identifiers.org/GO:0006633","https://identifiers.org/GO:0005737","https://identifiers.org/GO:0006915","https://identifiers.org/GO:0005783","https://identifiers.org/GO:0008610","https://identifiers.org/GO:0006629","https://identifiers.org/GO:0008219"],"go_kw":["fatty acid biosynthesis","cytoplasm","apoptosis","endoplasmic reticulum","lipid biosynthesis","lipid metabolism","cell death"],"integmet_study":"MTBLS1974","mesh_chemical_id":["https://identifiers.org/mesh:C019417","https://identifiers.org/mesh:D019301","https://identifiers.org/mesh:D008055","https://identifiers.org/mesh:D005229","https://identifiers.org/mesh:D010743"],"mesh_chemical_pubtator_kw":["D-2HG","oleic acid","lipid","MUFA","lipids","phospholipids","monounsaturated fatty acids"],"mesh_disease_id":["https://identifiers.org/mesh:D009369","https://identifiers.org/mesh:D005910"],"mesh_disease_pubtator_kw":["tumors","glioma","gliomas","tumor"],"mesh_gene_id":["https://identifiers.org/ncbigene:6319","https://identifiers.org/ncbigene:3417"],"mesh_gene_pubtator_kw":["stearyl-CoA desaturase","SCD","IDH1","IDH1WT"],"source_id":"https://identifiers.org/metabolights:MTBLS1974","study_findings":"IDH1 mutation-induced SCD overexpression alters lipid distribution, affecting organelle morphology.","study_observation":"Monounsaturated to polyunsaturated lipid imbalances in organelles.","study_summary":"IDH1 mutations cause organelle defects via lipid imbalance.","study_title_original":"IDH1 Mutations Induce Organelle Defects Via Dysregulated Phospholipids (CSHpos)"}