The functional role of OGDH for maintaining mitochondrial respiration and identity of primed human embryonic stem cells

Study details

Source ID

https://identifiers.org/metabolights:MTBLS4223

Title

The functional role of OGDH for maintaining mitochondrial respiration and identity of primed human embryonic stem cells

Summary

OGDH regulates mitochondrial respiration in primed hESCs.

Observation

Role of OGDH in mitochondrial respiration of primed hESCs.

Findings

OGDH is crucial for mitochondrial respiration and primed pluripotency in hESCs.

Disease terms

—

Gene terms

OGDH

Chemical terms

tricarboxylic acid, adenosine triphosphate, TCA, ATP

Organisms

Human, human

Raw data (JSON) Show

Also available at /api/study/https://identifiers.org/metabolights:MTBLS4223.

{
  "@type": "Dataset",
  "go_id": [
    "https://identifiers.org/GO:0022900",
    "https://identifiers.org/GO:0006099",
    "https://identifiers.org/GO:0008219",
    "https://identifiers.org/GO:0006096"
  ],
  "go_kw": [
    "electron transport chain (ETC)",
    "TCA cycle",
    "cell death",
    "glycolysis"
  ],
  "integmet_study": "MTBLS4223",
  "mesh_chemical_id": [
    "https://identifiers.org/mesh:D014233",
    "https://identifiers.org/mesh:D000255"
  ],
  "mesh_chemical_pubtator_kw": [
    "tricarboxylic acid",
    "adenosine triphosphate",
    "TCA",
    "ATP"
  ],
  "mesh_gene_id": [
    "https://identifiers.org/ncbigene:4967"
  ],
  "mesh_gene_pubtator_kw": [
    "OGDH"
  ],
  "ncbi_taxonomy_id": [
    "https://identifiers.org/taxonomy:9606"
  ],
  "ncbi_taxonomy_pubtator_kw": [
    "Human",
    "human"
  ],
  "source_id": "https://identifiers.org/metabolights:MTBLS4223",
  "study_findings": "OGDH is crucial for mitochondrial respiration and primed pluripotency in hESCs.",
  "study_observation": "Role of OGDH in mitochondrial respiration of primed hESCs.",
  "study_summary": "OGDH regulates mitochondrial respiration in primed hESCs.",
  "study_title_original": "The functional role of OGDH for maintaining mitochondrial respiration and identity of primed human embryonic stem cells"
}