Untargeted metabolomics identifies a plasma sphingolipid-related signature associated with lifestyle intervention in prepubertal children with obesity

Study details

Source ID

https://identifiers.org/metabolights:MTBLS423

Title

Untargeted metabolomics identifies a plasma sphingolipid-related signature associated with lifestyle intervention in prepubertal children with obesity

Summary

Lifestyle intervention affects sphingolipid metabolism in obese children.

Observation

Metabolic signatures in prepubertal children with obesity.

Findings

Decreased sphingolipid metabolites linked to improved HbA1c after intervention.

Disease terms

metabolic diseases, cardiovascular disease, type 2 diabetes, obesity

Gene terms

—

Chemical terms

sulfatide, Sphingolipid, sphingolipid, ceramide, sphingomyelin

Organisms

—

Raw data (JSON) Show

Also available at /api/study/https://identifiers.org/metabolights:MTBLS423.

{
  "@type": "Dataset",
  "integmet_study": "MTBLS423",
  "mesh_chemical_id": [
    "https://identifiers.org/mesh:D013433",
    "https://identifiers.org/mesh:D013107",
    "https://identifiers.org/mesh:D002518",
    "https://identifiers.org/mesh:D013109"
  ],
  "mesh_chemical_pubtator_kw": [
    "sulfatide",
    "Sphingolipid",
    "sphingolipid",
    "ceramide",
    "sphingomyelin"
  ],
  "mesh_disease_id": [
    "https://identifiers.org/mesh:D008659",
    "https://identifiers.org/mesh:D002318",
    "https://identifiers.org/mesh:D003924",
    "https://identifiers.org/mesh:D009765"
  ],
  "mesh_disease_pubtator_kw": [
    "metabolic diseases",
    "cardiovascular disease",
    "type 2 diabetes",
    "obesity"
  ],
  "source_id": "https://identifiers.org/metabolights:MTBLS423",
  "study_findings": "Decreased sphingolipid metabolites linked to improved HbA1c after intervention.",
  "study_observation": "Metabolic signatures in prepubertal children with obesity.",
  "study_summary": "Lifestyle intervention affects sphingolipid metabolism in obese children.",
  "study_title_original": "Untargeted metabolomics identifies a plasma sphingolipid-related signature associated with lifestyle intervention in prepubertal children with obesity"
}