topotecan

Metabolite details

Identifier

UCFGDBYHRUNTLO-QHCPKHFHSA-N

InChI Key

UCFGDBYHRUNTLO-QHCPKHFHSA-N

IUPAC name

(4S)-10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione

Preferred name

topotecan

INN name

topotecan

Synonym

Topotecan

ChEBI

CHEBI:63632

Reactome pathways

• No Reactome pathways listed for this metabolite.

Observed in studies

• Multi-Omics Analysis Reveals Disturbance of Nanosecond Pulsed Electric Field in the Serum Metabolic Spectrum and Gut Microbiota
• Changes and correlations of intestinal flora and liver metabolite profiles in mice with gallstones
• Integrated Metabolomics and Transcriptomics Analyses Reveal Anthocyanin and Carotenoid Biosynthesis Involved in Color Development in Willow Bark
• Alterations in the gut microbiota and metabolomics of seafarers after a six-month sea voyage
• Bacterial Pathogens Hijack the Innate Immune Response by Activation of the Reverse Transsulfuration Pathway.

Observed in differential profiles

• Control_vs_nsPEF_7_day
• Control_vs_Lithogenic_Diet
• Purple_vs_Green
• Control_0d_vs_Treatment_180d
• G1_Infected_Treated_vs_G2_Infected_Untreated