ponatinib — integMET

Metabolite details

Identifier: PHXJVRSECIGDHY-UHFFFAOYSA-N
InChI Key: PHXJVRSECIGDHY-UHFFFAOYSA-N
IUPAC name: 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide
Preferred name: ponatinib
INN name: ponatinib
Synonym: AP24534
ChEBI: CHEBI:78543

R-HSA-1280215 - Cytokine Signaling in Immune system
R-HSA-1433557 - Signaling by SCF-KIT
R-HSA-162582 - Signal Transduction
R-HSA-1643685 - Disease
R-HSA-168256 - Immune System
R-HSA-186797 - Signaling by PDGF
R-HSA-5213460 - RIPK1-mediated regulated necrosis
R-HSA-5218859 - Regulated Necrosis
R-HSA-5357801 - Programmed Cell Death
R-HSA-5663202 - Diseases of signal transduction by growth factor receptors and second messengers
R-HSA-5663205 - Infectious disease
R-HSA-5675482 - Regulation of necroptotic cell death
R-HSA-9006934 - Signaling by Receptor Tyrosine Kinases
R-HSA-9607240 - FLT3 Signaling
R-HSA-9669921 - KIT mutants bind TKIs
R-HSA-9669938 - Signaling by KIT in disease
R-HSA-9671555 - Signaling by PDGFR in disease
R-HSA-9674428 - PDGFR mutants bind TKIs
R-HSA-9679191 - Potential therapeutics for SARS
R-HSA-9679506 - SARS-CoV Infections
R-HSA-9682385 - FLT3 signaling in disease
R-HSA-9702506 - Drug resistance of FLT3 mutants
R-HSA-9702509 - FLT3 mutants bind TKIs
R-HSA-9702614 - ponatinib-resistant FLT3 mutants
R-HSA-9824446 - Viral Infection Pathways