sitagliptin

(3R)-3-amino-1-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)butan-1-one

MFFMDFFZMYYVKS-SECBINFHSA-N CHEBI:40237 4 Reactome links 3 studies

3 Observed studies

3 Observed diff profiles

4 Reactome pathways

Metabolite details

Identifier: MFFMDFFZMYYVKS-SECBINFHSA-N
InChI Key: MFFMDFFZMYYVKS-SECBINFHSA-N
IUPAC name: (3R)-3-amino-1-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)butan-1-one
Preferred name: sitagliptin
INN name: sitagliptine
Synonym: (2R)-4-OXO-4-[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-AMINE
ChEBI: CHEBI:40237

Reactome pathways

R-HSA-2980736 - Peptide hormone metabolism
R-HSA-381771 - Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)
R-HSA-392499 - Metabolism of proteins
R-HSA-400508 - Incretin synthesis, secretion, and inactivation

Observed in studies

Observed in differential profiles