metolazone

7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamide

AQCHWTWZEMGIFD-UHFFFAOYSA-N CHEBI:64354 4 Reactome links 1 studies

1 Observed studies

1 Observed diff profiles

4 Reactome pathways

Metabolite details

Identifier: AQCHWTWZEMGIFD-UHFFFAOYSA-N
InChI Key: AQCHWTWZEMGIFD-UHFFFAOYSA-N
IUPAC name: 7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamide
Preferred name: metolazone
INN name: metolazone
Synonym: 7-Chloro-1,2,3,4-tetrahydro-2-methyl-4-oxo-3-o-tolyl-6-quinazolinesulfonamide
ChEBI: CHEBI:64354

Reactome pathways

R-HSA-382551 - Transport of small molecules
R-HSA-425407 - SLC-mediated transmembrane transport
R-HSA-426117 - Cation-coupled Chloride cotransporters
R-HSA-9958790 - SLC-mediated transport of inorganic anions

Observed in studies

Diallyl disulfide (DADS) ameliorates intestinal Candida albicans infection by modulating the gut microbiota and metabolites and providing intestinal protection in mice

Observed in differential profiles

G1_PBS_vs_G2_DSS