Scientific_Control_MAM_vs_Knock-out_MAM

Scientific Control_MAM vs Knock-out_MAM

p-value ≤ 0.05 5 significant 2025-09-26 00:00:00 Study: MTBLS600
69 Total Features
5 Significant
0.05 p-value Threshold

Profile details

Identifier
MTBLS600_0001_00000001
Linked study
MTBLS600 — Deficient Endoplasmic Reticulum-Mitochondrial Phosphatidylserine Transfer Causes Liver Disease.
Comparison
Scientific Control_MAM vs Knock-out_MAM
Group A
Scientific control group for Mitochondria-associated Endoplasmic Reticulum Membrane. Provides baseline data for evaluating the effects of Mfn2 knock-out in MAM.
Group B
Knock-out group for Mitochondria-associated Endoplasmic Reticulum Membrane. Allows for the assessment of the impact of Mfn2 knock-out on MAM.
Total features tested
69
Significant features
5
p-value threshold
0.05
Ratio threshold (upper)
1.5
Ratio threshold (lower)
1/1.5
Date created
2025-09-26 00:00:00

Top hits

Metabolite ID (InChI Key) Name Direction Ratio p-value
FDWIGGGTKAUHLP-WZBLLWBYSA-N [(2S)-2-tetradecanoyloxy-3-[(Z)-tetradec-9-enoyl]oxypropyl] icosanoate up 4.304 0.0192
ASWBNKHCZGQVJV-HSZRJFAPSA-N PC(16:0/0:0) up 2.271 0.0226
RXKSKZZAOIRFLK-UQYDIMRYSA-N PE(14:0/20:2(11Z,14Z)) up 1.975 0.0155
XJLGATDALCZXFX-LSWZYRHBSA-N [(2R)-3-[2-aminoethoxy(hydroxy)phosphoryl]oxy-2-tetradecanoyloxypropyl] (13Z,16Z)-docosa-13,16-dienoate up 1.859 0.0436
RRVPPYNAZJRZFR-VYOBOKEXSA-N phosphatidylcholine(18:1ω9/16:0) up 1.736 0.0349