{"@type":"Dataset","go_id":["https://identifiers.org/GO:0006954","https://identifiers.org/GO:0008654","https://identifiers.org/GO:0001786"],"go_kw":["inflammation","phospholipid synthesis","phosphatidylserine binding"],"integmet_study":"MTBLS600","mesh_chemical_id":["https://identifiers.org/mesh:D010718","https://identifiers.org/mesh:C483858","https://identifiers.org/mesh:D010743"],"mesh_chemical_pubtator_kw":["phosphatidylserine","phosphatidylethanolamine","phospholipid","PE","Phosphatidylserine","PS"],"mesh_disease_id":["https://identifiers.org/mesh:D008107","https://identifiers.org/mesh:D007249","https://identifiers.org/mesh:D065626","https://identifiers.org/mesh:D005234","https://identifiers.org/mesh:D005235","https://identifiers.org/mesh:D006528","https://identifiers.org/mesh:D005355"],"mesh_disease_pubtator_kw":["liver disease","inflammation","Liver Disease","Non-alcoholic fatty liver","steatosis","non-alcoholic steatohepatitis","liver cancer","fibrosis","NASH"],"mesh_gene_id":["https://identifiers.org/ncbigene:9927","https://identifiers.org/ncbigene:170731"],"mesh_gene_pubtator_kw":["Mfn2","mitofusin 2"],"ncbi_taxonomy_id":["https://identifiers.org/taxonomy:10090","https://identifiers.org/taxonomy:9606"],"ncbi_taxonomy_pubtator_kw":["mice","mouse","patients"],"source_id":"https://identifiers.org/metabolights:MTBLS600","study_findings":"Mfn2 deficiency disrupts PS transfer, causing ER stress and liver disease.","study_observation":"Mfn2 expression in liver biopsies and mouse models of NASH.","study_summary":"Mfn2 deficiency causes liver disease via PS transfer disruption.","study_title_original":"Deficient Endoplasmic Reticulum-Mitochondrial Phosphatidylserine Transfer Causes Liver Disease."}