Diff Profiles › MTBLS1967_0001_00000001

U251_WT_ER_vs_U251_RC_ER

U251_WT_ER vs U251_RC_ER

p-value ≤ 0.05 2 significant 2025-09-26 00:00:00 Study: MTBLS1967
28 Total Features
2 Significant
0.05 p-value Threshold

Profile details

Identifier
MTBLS1967_0001_00000001
Linked study
MTBLS1967 — IDH1 Mutations Induce Organelle Defects Via Dysregulated Phospholipids (FA_HILICZ)
Comparison
U251_WT_ER vs U251_RC_ER
Group A
Wild type U251 cell line samples from the Endoplasmic Reticulum.. Provides baseline for comparison with IDH1 mutant samples.
Group B
IDH1 mutant (R132C) U251 cell line samples from the Endoplasmic Reticulum.. Allows assessment of IDH1 R132C mutation impact on ER morphology.
Total features tested
28
Significant features
2
p-value threshold
0.05
Ratio threshold (upper)
1.5
Ratio threshold (lower)
1/1.5
Date created
2025-09-26 00:00:00

Top hits

Metabolite ID (InChI Key) Name Direction Ratio p-value
ZDHCZVWCTKTBRY-UHFFFAOYSA-N 12-HYDROXYDODECANOIC ACID up 1.577 0.00878
MUCMKTPAZLSKTL-LLVKDONJSA-N (3R)-3-hydroxydodecanoic acid up 1.531 0.0432