Diff Profiles › MTBLS1295_0001_00000002

Healthy_vs_Cholestasis

Healthy vs Cholestasis

p-value ≤ 0.05 10 significant 2025-09-26 00:00:00 Study: MTBLS1295
31 Total Features
10 Significant
0.05 p-value Threshold

Profile details

Identifier
MTBLS1295_0001_00000002
Linked study
MTBLS1295 — Gut Microbiota Dysbiosis is Associated with Altered Bile Acid Metabolism in Infantile Cholestasis
Comparison
Healthy vs Cholestasis
Group A
Samples from healthy individuals.. Provides a baseline for understanding changes in gut microbiota and bile acid metabolism in disease conditions.
Group B
Samples from individuals with cholestasis.. Understanding the gut microbiota and bile acid metabolism in cholestasis.
Total features tested
31
Significant features
10
p-value threshold
0.05
Ratio threshold (upper)
1.5
Ratio threshold (lower)
1/1.5
Date created
2025-09-26 00:00:00

Top hits

Metabolite ID (InChI Key) Name Direction Ratio p-value
DXOCDBGWDZAYRQ-QPVZPPSOSA-N — down 0.06384 5.38e-05
DKPMWHFRUGMUKF-CRKPLTDNSA-N 3,6,7-trihydroxy-5β-cholan-24-oic acid down 0.05268 0.000257
BHQCQFFYRZLCQQ-OELDTZBJSA-N Cholic acid down 0.115 8.6e-05
OEKUSRBIIZNLHZ-DJDNIQJZSA-N 3-ketocholic acid down 0.06332 0.00146
RUDATBOHQWOJDD-BSWAIDMHSA-N anthropodesoxycholic acid down 0.281 3.33e-05
BHQCQFFYRZLCQQ-PGHAKIONSA-N 5α-cholic acid down 0.0351 0.0368
DKPMWHFRUGMUKF-KWXDGCAGSA-N γ-muricholic acid down 0.1345 0.00411
QBYUNVOYXHFVKC-GBURMNQMSA-N Taurolithocholic acid down 0.1001 0.0264
DKPMWHFRUGMUKF-NTPBNISXSA-N (3α,5β,6α,7β)-3,6,7-trihydroxycholan-24-oic acid down 0.2624 0.0302
KXGVEGMKQFWNSR-LLQZFEROSA-N Desoxycholsäure down 0.3519 0.0307