{"comparisonGroups":["Healthy","Cholestasis"],"dateCreated":"2025-09-26 00:00:00","display_title":"Gut microbiota: healthy vs cholestasis bile metabolism","group_a_title":"Samples from healthy individuals.. Provides a baseline for understanding changes in gut microbiota and bile acid metabolism in disease conditions.","group_b_title":"Samples from individuals with cholestasis.. Understanding the gut microbiota and bile acid metabolism in cholestasis.","id":"MTBLS1295_0001_00000002","pvalueThreshold":0.05,"ratioThresholdLower":"1/1.5","ratioThresholdUpper":1.5,"significantFeatures":10,"studyId":"MTBLS1295","studyUrl":"http://integmet.org/study/MTBLS1295","title":"Healthy_vs_Cholestasis","topHits":[{"chebi_id":"","direction":"down","inn_name":"","iupac_name":"","metabolite_id":"DXOCDBGWDZAYRQ-QPVZPPSOSA-N","pvalue":5.3792490394265034e-05,"ratio":0.0638432572012697,"synonym_name":""},{"chebi_id":"81298","direction":"down","inn_name":"","iupac_name":"3\u03b1,6\u03b2,7\u03b2-trihydroxy-5\u03b2-cholan-24-oic acid","metabolite_id":"DKPMWHFRUGMUKF-CRKPLTDNSA-N","pvalue":0.000256819693458,"ratio":0.0526789636218919,"synonym_name":"3,6,7-trihydroxy-5\u03b2-cholan-24-oic acid"},{"chebi_id":"16359","direction":"down","inn_name":"","iupac_name":"3\u03b1,7\u03b1,12\u03b1-trihydroxy-5\u03b2-cholan-24-oic acid","metabolite_id":"BHQCQFFYRZLCQQ-OELDTZBJSA-N","pvalue":8.595433076368723e-05,"ratio":0.1149917603929607,"synonym_name":"Cholic acid"},{"chebi_id":"88108","direction":"down","inn_name":"","iupac_name":"7\u03b1,12\u03b1-dihydroxy-3-oxo-5\u03b2-cholan-24-oic acid","metabolite_id":"OEKUSRBIIZNLHZ-DJDNIQJZSA-N","pvalue":0.0014588678030063,"ratio":0.0633228150654584,"synonym_name":"3-ketocholic acid"},{"chebi_id":"16755","direction":"down","inn_name":"","iupac_name":"3\u03b1,7\u03b1-dihydroxy-5\u03b2-cholan-24-oic acid","metabolite_id":"RUDATBOHQWOJDD-BSWAIDMHSA-N","pvalue":3.327190196775595e-05,"ratio":0.2809584227245884,"synonym_name":"anthropodesoxycholic acid"},{"chebi_id":"81308","direction":"down","inn_name":"","iupac_name":"3\u03b1,7\u03b1,12\u03b1-trihydroxy-5\u03b1-cholan-24-oic acid","metabolite_id":"BHQCQFFYRZLCQQ-PGHAKIONSA-N","pvalue":0.0367606786219227,"ratio":0.0351045011709992,"synonym_name":"5\u03b1-cholic acid"},{"chebi_id":"81244","direction":"down","inn_name":"","iupac_name":"3\u03b1,6\u03b1,7\u03b1-trihydroxy-5\u03b2-cholan-24-oic acid","metabolite_id":"DKPMWHFRUGMUKF-KWXDGCAGSA-N","pvalue":0.0041138092915355,"ratio":0.1345046970362044,"synonym_name":"\u03b3-muricholic acid"},{"chebi_id":"36259","direction":"down","inn_name":"","iupac_name":"2-[(3\u03b1-hydroxy-24-oxo-5\u03b2-cholan-24-yl)amino]ethanesulfonic acid","metabolite_id":"QBYUNVOYXHFVKC-GBURMNQMSA-N","pvalue":0.0264349849681495,"ratio":0.1000579400098052,"synonym_name":"Taurolithocholic acid"},{"chebi_id":"81299","direction":"down","inn_name":"","iupac_name":"3\u03b1,6\u03b1,7\u03b2-trihydroxy-5\u03b2-cholan-24-oic acid","metabolite_id":"DKPMWHFRUGMUKF-NTPBNISXSA-N","pvalue":0.0302240157174342,"ratio":0.2624158055848274,"synonym_name":"(3\u03b1,5\u03b2,6\u03b1,7\u03b2)-3,6,7-trihydroxycholan-24-oic acid"},{"chebi_id":"28834","direction":"down","inn_name":"","iupac_name":"3\u03b1,12\u03b1-dihydroxy-5\u03b2-cholan-24-oic acid","metabolite_id":"KXGVEGMKQFWNSR-LLQZFEROSA-N","pvalue":0.0306756131435783,"ratio":0.351879249097921,"synonym_name":"Desoxychols\u00e4ure"}],"totalFeatures":31}