Absolute quantitative lipidomics reveals lipidome-wide alterations in aging brain (Mouse brain NEG UPLC-MS assay)

Study details

Source ID

https://identifiers.org/metabolights:MTBLS495

Title

Absolute quantitative lipidomics reveals lipidome-wide alterations in aging brain (Mouse brain NEG UPLC-MS assay)

Summary

Lipidome changes in aging mouse brain studied.

Observation

Lipidome-wide changes in aging mouse brains

Findings

Link between aging and disordered lipid homeostasis; sphingolipids with longer acyl chains accumulate.

Disease terms

—

Gene terms

—

Chemical terms

lipid, sphingolipids, lipids, polyunsaturated fatty acids, Sphingolipids, glycerophospholipids

Organisms

mouse, human

Raw data (JSON) Show

Also available at /api/study/https://identifiers.org/metabolights:MTBLS495.

{
  "@type": "Dataset",
  "go_id": [
    "https://identifiers.org/GO:0006629"
  ],
  "go_kw": [
    "lipid metabolism"
  ],
  "integmet_study": "MTBLS495",
  "mesh_chemical_id": [
    "https://identifiers.org/mesh:D008055",
    "https://identifiers.org/mesh:D013107",
    "https://identifiers.org/mesh:D005231",
    "https://identifiers.org/mesh:D020404"
  ],
  "mesh_chemical_pubtator_kw": [
    "lipid",
    "sphingolipids",
    "lipids",
    "polyunsaturated fatty acids",
    "Sphingolipids",
    "glycerophospholipids"
  ],
  "ncbi_taxonomy_id": [
    "https://identifiers.org/taxonomy:10090",
    "https://identifiers.org/taxonomy:9606"
  ],
  "ncbi_taxonomy_pubtator_kw": [
    "mouse",
    "human"
  ],
  "source_id": "https://identifiers.org/metabolights:MTBLS495",
  "study_findings": "Link between aging and disordered lipid homeostasis; sphingolipids with longer acyl chains accumulate.",
  "study_observation": "Lipidome-wide changes in aging mouse brains",
  "study_summary": "Lipidome changes in aging mouse brain studied.",
  "study_title_original": "Absolute quantitative lipidomics reveals lipidome-wide alterations in aging brain (Mouse brain NEG UPLC-MS assay)"
}