Specific decorations of 17-hydroxygeranyllinalool diterpene glycosides solve the autotoxicity problem of chemical defense in Nicotiana attenuata.

Study details

Source ID

https://identifiers.org/metabolights:MTBLS1819

Title

Specific decorations of 17-hydroxygeranyllinalool diterpene glycosides solve the autotoxicity problem of chemical defense in Nicotiana attenuata.

Summary

HGL-DTG biosynthesis and autotoxicity in Nicotiana attenuata.

Observation

Biosynthetic pathway of HGL-DTGs in Nicotiana attenuata.

Findings

Glucosylation and rhamnosylation solve autotoxicity and enhance defense.

Disease terms

phytotoxic effect

Gene terms

geranylgeranyl diphosphate synthase

Chemical terms

jasmonate, 17-hydroxygeranyllinalool, aglycone, 17-HGL, UDP-glucose

Organisms

Manduca sexta, Nicotiana attenuata, tobacco, tobacco hornworm

Raw data (JSON) Show

Also available at /api/study/https://identifiers.org/metabolights:MTBLS1819.

{
  "@type": "Dataset",
  "go_id": [
    "https://identifiers.org/GO:0009058",
    "https://identifiers.org/GO:0070085"
  ],
  "go_kw": [
    "biosynthesis",
    "glycosylation"
  ],
  "integmet_study": "MTBLS1819",
  "mesh_chemical_id": [
    "https://identifiers.org/mesh:C011006",
    "https://identifiers.org/mesh:C000719075",
    "https://identifiers.org/mesh:C458179",
    "https://identifiers.org/mesh:D014532"
  ],
  "mesh_chemical_pubtator_kw": [
    "jasmonate",
    "17-hydroxygeranyllinalool",
    "aglycone",
    "17-HGL",
    "UDP-glucose"
  ],
  "mesh_disease_id": [
    "https://identifiers.org/mesh:D065606"
  ],
  "mesh_disease_pubtator_kw": [
    "phytotoxic effect"
  ],
  "mesh_gene_id": [
    "https://identifiers.org/ncbigene:107774226"
  ],
  "mesh_gene_pubtator_kw": [
    "geranylgeranyl diphosphate synthase"
  ],
  "ncbi_taxonomy_id": [
    "https://identifiers.org/taxonomy:7130",
    "https://identifiers.org/taxonomy:49451",
    "https://identifiers.org/taxonomy:4097"
  ],
  "ncbi_taxonomy_pubtator_kw": [
    "Manduca sexta",
    "Nicotiana attenuata",
    "tobacco",
    "tobacco hornworm"
  ],
  "source_id": "https://identifiers.org/metabolights:MTBLS1819",
  "study_findings": "Glucosylation and rhamnosylation solve autotoxicity and enhance defense.",
  "study_observation": "Biosynthetic pathway of HGL-DTGs in Nicotiana attenuata.",
  "study_summary": "HGL-DTG biosynthesis and autotoxicity in Nicotiana attenuata.",
  "study_title_original": "Specific decorations of 17-hydroxygeranyllinalool diterpene glycosides solve the autotoxicity problem of chemical defense in Nicotiana attenuata."
}