sorafenib — integMET

Metabolite details

Identifier: MLDQJTXFUGDVEO-UHFFFAOYSA-N
InChI Key: MLDQJTXFUGDVEO-UHFFFAOYSA-N
IUPAC name: 4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-N-methylpyridine-2-carboxamide
Preferred name: sorafenib
INN name: sorafénib
Synonym: N-(4-Chloro-3-(trifluoromethyl)phenyl)-N'-(4-(2-(N-methylcarbamoyl)-4-pyridyloxy)phenyl)urea
ChEBI: CHEBI:50924

R-HSA-1280215 - Cytokine Signaling in Immune system
R-HSA-1433557 - Signaling by SCF-KIT
R-HSA-162582 - Signal Transduction
R-HSA-1643685 - Disease
R-HSA-168256 - Immune System
R-HSA-186797 - Signaling by PDGF
R-HSA-5213460 - RIPK1-mediated regulated necrosis
R-HSA-5218859 - Regulated Necrosis
R-HSA-5357801 - Programmed Cell Death
R-HSA-5663202 - Diseases of signal transduction by growth factor receptors and second messengers
R-HSA-5675482 - Regulation of necroptotic cell death
R-HSA-6802948 - Signaling by high-kinase activity BRAF mutants
R-HSA-6802957 - Oncogenic MAPK signaling
R-HSA-9006934 - Signaling by Receptor Tyrosine Kinases
R-HSA-9607240 - FLT3 Signaling
R-HSA-9669921 - KIT mutants bind TKIs
R-HSA-9669936 - Sorafenib-resistant KIT mutants
R-HSA-9669937 - Drug resistance of KIT mutants
R-HSA-9669938 - Signaling by KIT in disease
R-HSA-9671555 - Signaling by PDGFR in disease
R-HSA-9674404 - Sorafenib-resistant PDGFR mutants
R-HSA-9674415 - Drug resistance of PDGFR mutants
R-HSA-9674428 - PDGFR mutants bind TKIs
R-HSA-9682385 - FLT3 signaling in disease
R-HSA-9702506 - Drug resistance of FLT3 mutants
R-HSA-9702509 - FLT3 mutants bind TKIs
R-HSA-9702624 - sorafenib-resistant FLT3 mutants