{"chebi_id":"50924","chebi_name":"sorafenib","chebi_synonyms":["soraf\u00e9nib","N-(4-Chloro-3-(trifluoromethyl)phenyl)-N'-(4-(2-(N-methylcarbamoyl)-4-pyridyloxy)phenyl)urea","4-(4-((((4-Chloro-3-(trifluoromethyl)phenyl)amino)carbonyl)amino)phenoxy)-N-methyl-2-pyridinecarboxamide","4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-N-methylpyridine-2-carboxamide","sorafenibum"],"diffprof_id_observed":["MTBLS2406_0001_00000009"],"diffprof_id_var_observed":[],"inchikey":"MLDQJTXFUGDVEO-UHFFFAOYSA-N","inn_name":"soraf\u00e9nib","iupac_name":"4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-<em>N</em>-methylpyridine-2-carboxamide","num_study_observed":1,"reactome_ids":["R-HSA-1280215","R-HSA-1433557","R-HSA-162582","R-HSA-1643685","R-HSA-168256","R-HSA-186797","R-HSA-5213460","R-HSA-5218859","R-HSA-5357801","R-HSA-5663202","R-HSA-5675482","R-HSA-6802948","R-HSA-6802957","R-HSA-9006934","R-HSA-9607240","R-HSA-9669921","R-HSA-9669936","R-HSA-9669937","R-HSA-9669938","R-HSA-9671555","R-HSA-9674404","R-HSA-9674415","R-HSA-9674428","R-HSA-9682385","R-HSA-9702506","R-HSA-9702509","R-HSA-9702624"],"reactome_names":["Cytokine Signaling in Immune system","Signaling by SCF-KIT","Signal Transduction","Disease","Immune System","Signaling by PDGF","RIPK1-mediated regulated necrosis","Regulated Necrosis","Programmed Cell Death","Diseases of signal transduction by growth factor receptors and second messengers","Regulation of necroptotic cell death","Signaling by high-kinase activity BRAF mutants","Oncogenic MAPK signaling","Signaling by Receptor Tyrosine Kinases","FLT3 Signaling","KIT mutants bind TKIs","Sorafenib-resistant KIT mutants","Drug resistance of KIT mutants","Signaling by KIT in disease","Signaling by PDGFR in disease","Sorafenib-resistant PDGFR mutants","Drug resistance of PDGFR mutants","PDGFR mutants bind TKIs","FLT3 signaling in disease","Drug resistance of FLT3 mutants","FLT3 mutants bind TKIs","sorafenib-resistant FLT3 mutants"],"study_id_observed":["MTBLS2406"],"study_id_var_observed":[],"synonym_name":"<em>N</em>-(4-Chloro-3-(trifluoromethyl)phenyl)-<em>N</em>'-(4-(2-(<em>N</em>-methylcarbamoyl)-4-pyridyloxy)phenyl)urea"}