4-HDoHE

Metabolite details

Identifier

IFRKCNPQVIJFAQ-PQVBWYSWSA-N

InChI Key

IFRKCNPQVIJFAQ-PQVBWYSWSA-N

IUPAC name

(5E,7Z,10Z,13Z,16Z,19Z)-4-hydroxydocosa-5,7,10,13,16,19-hexaenoic acid

Preferred name

4-HDoHE

INN name

—

Synonym

(+/-)-4-hydroxy-5E,7Z,10Z,13Z,16Z,19Z-docosahexaenoic acid

ChEBI

CHEBI:72624

Reactome pathways

• No Reactome pathways listed for this metabolite.

Observed in studies

• Essential omega-3 fatty acids tune microglial phagocytosis of synaptic elements in the developing brain
• Intergenerational Association of Gut Microbiota and Metabolism between Perinatal Folic Acid Metabolism and Neural Tube Defects (Feces metabolomics)
• Interaction between Cervical Microbiota and Host Gene Regulation in Caesarean Section Scar Diverticulum

Observed in differential profiles

• n-3_PUFA_sufficient_vs_n-3_PUFA_deficient
• Normal_vs_Neural_Tube_Defect
• Control_vs_CSD