G1_Untreated_Control_vs_G2_2DG

Untreated Control vs 2DG

p-value ≤ 0.05 8 significant 2025-09-26 00:00:00 Study: MTBLS858
13 Total Features
8 Significant
0.05 p-value Threshold

Profile details

Identifier
MTBLS858_0002_00000001
Linked study
MTBLS858 — Inhibition of glycolysis and mitochondrial respiration promotes radiosensitisation of neuroblastoma and glioma cells
Comparison
Untreated Control vs 2DG
Group A
Baseline control group with no treatment applied.. Provides a reference point for evaluating the effects of treatments.
Group B
Group treated with 2-deoxy-D-glucose (2DG).. Evaluates the effect of 2DG on radiosensitivity.
Total features tested
13
Significant features
8
p-value threshold
0.05
Ratio threshold (upper)
1.5
Ratio threshold (lower)
1/1.5
Date created
2025-09-26 00:00:00

Top hits

Metabolite ID (InChI Key) Name Direction Ratio p-value
LXJXRIRHZLFYRP-UHFFFAOYSA-N Glyceraldehyde 3-phosphate up 1e+06 2.1e-07
UQJFZAAGZAYVKZ-CERMHHMHSA-N 2-Deoxy-D-glucose 6-phosphate down 0.002939 4.3e-06
NBSCHQHZLSJFNQ-GASJEMHNSA-N Glc6P down 0.009058 2.32e-05
WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-Glucose down 0.01905 5.19e-06
BJEPYKJPYRNKOW-UHFFFAOYSA-N 2-Hydroxysuccinic acid up 3.722 6.91e-06
DTBNBXWJWCWCIK-UHFFFAOYSA-N PEP up 3.13 0.00287
KRKNYBCHXYNGOX-UHFFFAOYSA-N Citronensäure up 1.785 0.000509
ODBLHEXUDAPZAU-UHFFFAOYSA-N Isocitric acid up 1.785 0.000509