Normal_Heart_Development_vs_Ventricular_Septal_Defect

Normal_Heart_Development vs Ventricular_Septal_Defect

p-value ≤ 0.05 10 significant 2025-09-26 00:00:00 Study: MTBLS6982
11 Total Features
10 Significant
0.05 p-value Threshold

Profile details

Identifier
MTBLS6982_0001_00000001
Linked study
MTBLS6982 — Gestational palmitic acid suppresses embryonic GATA-binding protein 4 signaling and causes congenital heart disease
Comparison
Normal_Heart_Development vs Ventricular_Septal_Defect
Group A
Samples from individuals with normal heart development.. Provides a baseline for understanding metabolic changes associated with congenital heart defects.
Group B
Samples from individuals with ventricular septal defect.. Understanding the metabolic differences in individuals with ventricular septal defect compared to normal heart development.
Total features tested
11
Significant features
10
p-value threshold
0.05
Ratio threshold (upper)
1.5
Ratio threshold (lower)
1/1.5
Date created
2025-09-26 00:00:00

Top hits

Metabolite ID (InChI Key) Name Direction Ratio p-value
ZQPPMHVWECSIRJ-KTKRTIGZSA-N Oleate up 1.729 8.57e-05
BITHHVVYSMSWAG-KTKRTIGZSA-N <i>cis</i>-Δ<small><sup>11</small></sup>-eicosenoic acid up 1.821 0.00028
YZXBAPSDXZZRGB-DOFZRALJSA-N Arachidonate up 1.933 0.00179
IPCSVZSSVZVIGE-UHFFFAOYSA-N <em>n</em>-hexadecoic acid up 1.697 0.000416
OYHQOLUKZRVURQ-HZJYTTRNSA-N Linoleic acid up 1.681 0.00106
QIQXTHQIDYTFRH-UHFFFAOYSA-N Stearinsäure up 1.571 0.000632
GWHCXVQVJPWHRF-KTKRTIGZSA-N <i>cis</i>-15-tetracosenoic acid up 1.875 0.00553
QZZGJDVWLFXDLK-UHFFFAOYSA-N CH<small><sub>3</sub></small>‒[CH<small><sub>2</sub></small>]<small><sub>22</sub></small>‒COOH up 1.848 0.00552
DTOSIQBPPRVQHS-PDBXOOCHSA-N (9,12,15)-linolenic acid up 1.629 0.00378
VKOBVWXKNCXXDE-UHFFFAOYSA-N C20:0 up 1.549 0.0074