Diff Profiles › MTBLS4307_0001_00000002

Control_Cytoplasm_vs_TFAM_Knockdown_Cytoplasm

Control_Cytoplasm vs TFAM_Knockdown_Cytoplasm

p-value ≤ 0.05 16 significant 2025-09-26 00:00:00 Study: MTBLS4307
24 Total Features
16 Significant
0.05 p-value Threshold

Profile details

Identifier
MTBLS4307_0001_00000002
Linked study
MTBLS4307 — TFAM loss induces nuclear actin assembly upon mDia2 malonylation to promote liver cancer metastasis.
Comparison
Control_Cytoplasm vs TFAM_Knockdown_Cytoplasm
Group A
Control group with samples from the cytoplasm. Provides baseline data for cytoplasmic conditions in control genotype
Group B
TFAM knockdown group with samples from the cytoplasm. Allows assessment of TFAM knockdown effects in the cytoplasm
Total features tested
24
Significant features
16
p-value threshold
0.05
Ratio threshold (upper)
1.5
Ratio threshold (lower)
1/1.5
Date created
2025-09-26 00:00:00

Top hits

Metabolite ID (InChI Key) Name Direction Ratio p-value
KTVPXOYAKDPRHY-AIHAYLRMSA-N 5-<em>O</em>-phosphono-α-<small>D</small>-ribofuranose down 0.03891 6.18e-08
QGWNDRXFNXRZMB-UUOKFMHZSA-N Guanosine diphosphate up 30.24 1.37e-07
HXXFSFRBOHSIMQ-VFUOTHLCSA-N ALPHA-D-GLUCOSE-1-PHOSPHATE up 4.784 3.68e-10
VZCYOOQTPOCHFL-OWOJBTEDSA-N (2<i>E</i>)-2-butenedioic acid up 49.52 0.00101
UDMBCSSLTHHNCD-KQYNXXCUSA-N Adenosine-5'-monophosphoric acid up 7.542 4.9e-06
ZKHQWZAMYRWXGA-KQYNXXCUSA-N Adenosine 5'-triphosphate up 5.031 9.71e-06
HSCJRCZFDFQWRP-RDKQLNKOSA-N UDP-glucose down 0.4035 5.84e-09
BOPGDPNILDQYTO-NNYOXOHSSA-N 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE up 2.337 3.27e-09
NBSCHQHZLSJFNQ-GASJEMHNSA-N Glc6P down 0.2998 2.19e-06
GSXOAOHZAIYLCY-HSUXUTPPSA-N D-Fructose 6-phosphate down 0.1731 0.000913