Susceptible_vs_Resistant

Susceptible vs Resistant

p-value ≤ 0.05 11 significant 2025-09-26 00:00:00 Study: MTBLS4132
18 Total Features
11 Significant
0.05 p-value Threshold

Profile details

Identifier
MTBLS4132_0001_00000003
Linked study
MTBLS4132 — Cell Membrane Remodeling Mediates Polymyxin B Resistance in <i>Klebsiella pneumoniae</i>: An Integrated Proteomics and Metabolomics Study.
Comparison
Susceptible vs Resistant
Group A
Experimental samples of Klebsiella pneumoniae susceptible to Polymyxin B.. Serves as the reference point for comparing resistant strains.
Group B
Experimental samples of Klebsiella pneumoniae resistant to Polymyxin B.. Allows for the study of resistance mechanisms and comparison with susceptible strains.
Total features tested
18
Significant features
11
p-value threshold
0.05
Ratio threshold (upper)
1.5
Ratio threshold (lower)
1/1.5
Date created
2025-09-26 00:00:00

Top hits

Metabolite ID (InChI Key) Name Direction Ratio p-value
BTUSGZZCQZACPT-YYZTVXDQSA-N hexadecasphingosine down 0.2227 1.35e-09
AERBNCYCJBRYDG-KSZLIROESA-N 4-D-Hydroxysphinganine down 0.1641 4.67e-06
JDDPIZZUPYSPAY-ZSQVXSMXSA-N [(2S,3S,4R)-3,4-dihydroxy-2-(2-hydroxyicosanoylamino)octadecyl] [(5R)-2,3,4,5,6-pentahydroxycyclohexyl] hydrogen phosphate down 0.179 9.02e-06
UHPXXKLAACDXGS-UHFFFAOYSA-N N-(2-hydroxyethyl)pentadecanamide down 0.158 0.000404
YQBIRCWGTRXVEA-NUZFNMCPSA-N PSer(16:1n7/16:0) down 0.5112 1.95e-05
ZBCBWPMODOFKDW-UHFFFAOYSA-N <em>N</em>,<em>N</em>-di(hydroxyethyl)amine down 0.515 2.42e-05
QKISPFFHFYCBQG-ZWXJPIIXSA-N (2S)-2-amino-3-[[(2R)-2-dodecanoyloxy-3-hexadecoxypropoxy]-hydroxyphosphoryl]oxypropanoic acid down 0.6536 0.000248
NKSOSPOXQKNIKJ-CLFAGFIQSA-N 2-[(Z)-octadec-9-enoyl]oxyethyl (Z)-octadec-9-enoate up 1.606 0.00383
QVUWNEQTPVMHQT-RLSIPVDZSA-N [(2R)-1-[2-aminoethoxy(hydroxy)phosphoryl]oxy-3-[(Z)-hexadec-9-enoyl]oxypropan-2-yl] (Z)-octadec-11-enoate down 0.5992 0.00852
YHFQOJAJZJQFEQ-MHBUEFIPSA-N (2S)-2-amino-3-[[(2R)-2-dodecanoyloxy-3-[(Z)-octadec-1-enoxy]propoxy]-hydroxyphosphoryl]oxypropanoic acid up 1.545 0.0172