Gut microbiota-bile acid crosstalk contributes to the rebound weight gain after calorie restriction in mice

Study details

Source ID

https://identifiers.org/metabolights:MTBLS4431

Title

Gut microbiota-bile acid crosstalk contributes to the rebound weight gain after calorie restriction in mice

Summary

Gut microbiota affects weight regain post-calorie restriction.

Observation

Gut microbiota and bile acid changes after calorie restriction and high-fat diet.

Findings

Parabacteroides distasonis and bile acids affect weight regain via thermogenesis.

Disease terms

calorie restriction, Calorie restriction, weight gain, weight reduction

Gene terms

GLP-1, UCP1

Chemical terms

bile acid, lithocholic acid, ursodeoxycholic acid

Organisms

mice, Parabacteroides distasonis

Raw data (JSON) Show

Also available at /api/study/https://identifiers.org/metabolights:MTBLS4431.

{
  "@type": "Dataset",
  "go_id": [
    "https://identifiers.org/GO:0008152"
  ],
  "go_kw": [
    "metabolism"
  ],
  "integmet_study": "MTBLS4431",
  "mesh_chemical_id": [
    "https://identifiers.org/mesh:D001647",
    "https://identifiers.org/mesh:D008095",
    "https://identifiers.org/mesh:D014580"
  ],
  "mesh_chemical_pubtator_kw": [
    "bile acid",
    "lithocholic acid",
    "ursodeoxycholic acid"
  ],
  "mesh_disease_id": [
    "https://identifiers.org/mesh:D002313",
    "https://identifiers.org/mesh:D015430",
    "https://identifiers.org/mesh:D015431"
  ],
  "mesh_disease_pubtator_kw": [
    "calorie restriction",
    "Calorie restriction",
    "weight gain",
    "weight reduction"
  ],
  "mesh_gene_id": [
    "https://identifiers.org/ncbigene:14526",
    "https://identifiers.org/ncbigene:22227"
  ],
  "mesh_gene_pubtator_kw": [
    "GLP-1",
    "UCP1"
  ],
  "ncbi_taxonomy_id": [
    "https://identifiers.org/taxonomy:10090",
    "https://identifiers.org/taxonomy:823"
  ],
  "ncbi_taxonomy_pubtator_kw": [
    "mice",
    "Parabacteroides distasonis"
  ],
  "source_id": "https://identifiers.org/metabolights:MTBLS4431",
  "study_findings": "Parabacteroides distasonis and bile acids affect weight regain via thermogenesis.",
  "study_observation": "Gut microbiota and bile acid changes after calorie restriction and high-fat diet.",
  "study_summary": "Gut microbiota affects weight regain post-calorie restriction.",
  "study_title_original": "Gut microbiota-bile acid crosstalk contributes to the rebound weight gain after calorie restriction in mice"
}