Integrative Modeling of Quantitative Plasma Lipoprotein, Metabolic, and Amino Acid Data Reveals a Multiorgan Pathological Signature of SARS-CoV-2 Infection

Study details

Source ID

https://identifiers.org/metabolights:MTBLS2014

Title

Integrative Modeling of Quantitative Plasma Lipoprotein, Metabolic, and Amino Acid Data Reveals a Multiorgan Pathological Signature of SARS-CoV-2 Infection

Summary

Metabolic effects of SARS-CoV-2 on plasma analyzed.

Observation

Quantitative plasma lipoprotein, metabolic, and amino acid data

Findings

Systemic signature of SARS-CoV-2 includes liver dysfunction, dyslipidaemia, diabetes, coronary heart disease risk.

Disease terms

coronary heart disease, diabetes, SARS-CoV-2 Infection, inflammation, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, dyslipidemia, liver dysfunction, COVID-19, coronavirus disease 19, SARS-CoV-2 infection, coronary artery disease

Gene terms

Apolipoprotein A1

Chemical terms

kynurenine, tryptophan, glucose, amines, triglycerides

Organisms

patients, human

Raw data (JSON) Show

Also available at /api/study/https://identifiers.org/metabolights:MTBLS2014.

{
  "@type": "Dataset",
  "integmet_study": "MTBLS2014",
  "mesh_chemical_id": [
    "https://identifiers.org/mesh:D007737",
    "https://identifiers.org/mesh:D014364",
    "https://identifiers.org/mesh:D005947",
    "https://identifiers.org/mesh:D000588",
    "https://identifiers.org/mesh:D014280"
  ],
  "mesh_chemical_pubtator_kw": [
    "kynurenine",
    "tryptophan",
    "glucose",
    "amines",
    "triglycerides"
  ],
  "mesh_disease_id": [
    "https://identifiers.org/mesh:D003327",
    "https://identifiers.org/mesh:D003920",
    "https://identifiers.org/mesh:D000086382",
    "https://identifiers.org/mesh:D007249",
    "https://identifiers.org/mesh:D050171",
    "https://identifiers.org/mesh:D017093",
    "https://identifiers.org/mesh:D003324"
  ],
  "mesh_disease_pubtator_kw": [
    "coronary heart disease",
    "diabetes",
    "SARS-CoV-2 Infection",
    "inflammation",
    "severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection",
    "dyslipidemia",
    "liver dysfunction",
    "COVID-19",
    "coronavirus disease 19",
    "SARS-CoV-2 infection",
    "coronary artery disease"
  ],
  "mesh_gene_id": [
    "https://identifiers.org/ncbigene:335"
  ],
  "mesh_gene_pubtator_kw": [
    "Apolipoprotein A1"
  ],
  "ncbi_taxonomy_id": [
    "https://identifiers.org/taxonomy:9606"
  ],
  "ncbi_taxonomy_pubtator_kw": [
    "patients",
    "human"
  ],
  "source_id": "https://identifiers.org/metabolights:MTBLS2014",
  "study_findings": "Systemic signature of SARS-CoV-2 includes liver dysfunction, dyslipidaemia, diabetes, coronary heart disease risk.",
  "study_observation": "Quantitative plasma lipoprotein, metabolic, and amino acid data",
  "study_summary": "Metabolic effects of SARS-CoV-2 on plasma analyzed.",
  "study_title_original": "Integrative Modeling of Quantitative Plasma Lipoprotein, Metabolic, and Amino Acid Data Reveals a Multiorgan Pathological Signature of SARS-CoV-2 Infection"
}