Multiomics of synaptic junctions reveals altered lipid metabolism and signaling following environmental enrichment

Study details

Source ID

https://identifiers.org/metabolights:MTBLS1531

Title

Multiomics of synaptic junctions reveals altered lipid metabolism and signaling following environmental enrichment

Summary

Multiomics reveals lipid metabolism changes in synapses.

Observation

Interplay of proteins and lipids in synaptic signal transduction

Findings

Reduced endocannabinoid synthesis linked to increased AMPAR expression in enriched environment.

Disease terms

—

Gene terms

Cannabinoid-receptor 1

Chemical terms

endocannabinoid, lipids, lipid

Organisms

rat, mouse, mice

Raw data (JSON) Show

Also available at /api/study/https://identifiers.org/metabolights:MTBLS1531.

{
  "@type": "Dataset",
  "go_id": [
    "https://identifiers.org/GO:0023052",
    "https://identifiers.org/GO:0007268"
  ],
  "go_kw": [
    "signaling",
    "neurotransmission"
  ],
  "integmet_study": "MTBLS1531",
  "mesh_chemical_id": [
    "https://identifiers.org/mesh:D063388",
    "https://identifiers.org/mesh:D008055"
  ],
  "mesh_chemical_pubtator_kw": [
    "endocannabinoid",
    "lipids",
    "lipid"
  ],
  "mesh_gene_id": [
    "https://identifiers.org/ncbigene:12801"
  ],
  "mesh_gene_pubtator_kw": [
    "Cannabinoid-receptor 1"
  ],
  "ncbi_taxonomy_id": [
    "https://identifiers.org/taxonomy:10116",
    "https://identifiers.org/taxonomy:10090"
  ],
  "ncbi_taxonomy_pubtator_kw": [
    "rat",
    "mouse",
    "mice"
  ],
  "source_id": "https://identifiers.org/metabolights:MTBLS1531",
  "study_findings": "Reduced endocannabinoid synthesis linked to increased AMPAR expression in enriched environment.",
  "study_observation": "Interplay of proteins and lipids in synaptic signal transduction",
  "study_summary": "Multiomics reveals lipid metabolism changes in synapses.",
  "study_title_original": "Multiomics of synaptic junctions reveals altered lipid metabolism and signaling following environmental enrichment"
}