The genome analysis of Tripterygium wilfordii reveals TwCYP712K1 and TwCYP712K2 responsible for oxidation of friedelin in celastrol biosynthesis pathway

Study details

Source ID

https://identifiers.org/metabolights:MTBLS1080

Title

The genome analysis of Tripterygium wilfordii reveals TwCYP712K1 and TwCYP712K2 responsible for oxidation of friedelin in celastrol biosynthesis pathway

Summary

Genome analysis of Tripterygium wilfordii for celastrol biosynthesis.

Observation

Genome, transcriptome, and metabolite analyses of T. wilfordii.

Findings

TwCYP712K1 and TwCYP712K2 oxidize friedelin in celastrol biosynthesis.

Disease terms

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Gene terms

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Chemical terms

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Organisms

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Raw data (JSON) Show

Also available at /api/study/https://identifiers.org/metabolights:MTBLS1080.

{
  "@type": "Dataset",
  "go_id": [
    "https://identifiers.org/GO:0009058"
  ],
  "go_kw": [
    "biosynthesis"
  ],
  "integmet_study": "MTBLS1080",
  "source_id": "https://identifiers.org/metabolights:MTBLS1080",
  "study_findings": "TwCYP712K1 and TwCYP712K2 oxidize friedelin in celastrol biosynthesis.",
  "study_observation": "Genome, transcriptome, and metabolite analyses of T. wilfordii.",
  "study_summary": "Genome analysis of Tripterygium wilfordii for celastrol biosynthesis.",
  "study_title_original": "The genome analysis of Tripterygium wilfordii reveals TwCYP712K1 and TwCYP712K2 responsible for oxidation of friedelin in celastrol biosynthesis pathway"
}