tanespimycin

(4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-19-(prop-2-en-1-ylamino)-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate

AYUNIORJHRXIBJ-TXHRRWQRSA-N CHEBI:64153 7 Reactome links 1 studies

1 Observed studies

1 Observed diff profiles

7 Reactome pathways

Metabolite details

Identifier: AYUNIORJHRXIBJ-TXHRRWQRSA-N
InChI Key: AYUNIORJHRXIBJ-TXHRRWQRSA-N
IUPAC name: (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-19-(prop-2-en-1-ylamino)-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
Preferred name: tanespimycin
INN name: tanespimycinum
Synonym: 17-Demethoxy-17-allylamino geldanamycin
ChEBI: CHEBI:64153

Reactome pathways

R-HSA-1236382 - Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants
R-HSA-1643685 - Disease
R-HSA-1643713 - Signaling by EGFR in Cancer
R-HSA-5637810 - Constitutive Signaling by EGFRvIII
R-HSA-5637812 - Signaling by EGFRvIII in Cancer
R-HSA-5637815 - Signaling by Ligand-Responsive EGFR Variants in Cancer
R-HSA-5663202 - Diseases of signal transduction by growth factor receptors and second messengers

Observed in studies

Integrated Metabolomics and Transcriptomics Analyses Reveal Anthocyanin and Carotenoid Biosynthesis Involved in Color Development in Willow Bark

Observed in differential profiles

Purple_vs_Green