Diff Profiles › MTBLS2262_0001_00000008

Control_vs_AONFH_Stage_III_IV

Control vs AONFH_Stage_III_IV

p-value ≤ 0.05 33 significant 2025-09-26 00:00:00 Study: MTBLS2262
269 Total Features
33 Significant
0.05 p-value Threshold

Profile details

Identifier
MTBLS2262_0001_00000008
Linked study
MTBLS2262 — Global analysis of plasma lipidomics reveals altered lipid signatures in patients with osteonecrosis of the femoral head
Comparison
Control vs AONFH_Stage_III_IV
Group A
Healthy control samples. Provides baseline lipidome profile for comparison with ONFH samples.
Group B
Alcohol-induced ONFH at stages III/IV. Helps in understanding advanced lipidome changes in alcohol-induced ONFH.
Total features tested
269
Significant features
33
p-value threshold
0.05
Ratio threshold (upper)
1.5
Ratio threshold (lower)
1/1.5
Date created
2025-09-26 00:00:00

Top hits

Metabolite ID (InChI Key) Name Direction Ratio p-value
UGAGPNKCDRTDHP-UHFFFAOYSA-N 16-OH 16:0 up 2.595 0.000131
KBDCFYFMQOAHAN-WUQMUQDBSA-N PG(18:2/18:1) up 2.327 6.61e-05
FEWJPZIEWOKRBE-UHFFFAOYSA-N 2,3-dihydroxysuccinic acid up 2.443 0.00017
SGQIECCWAOPTNL-LEFPGAKQSA-N [(2R)-1-[2-aminoethoxy(hydroxy)phosphoryl]oxy-3-[(11Z,14Z)-icosa-11,14-dienoyl]oxypropan-2-yl] (4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoate down 0.4206 0.000292
MWOOGOJBHIARFG-UHFFFAOYSA-N 4-Hydroxy-3-methoxy-benzaldehyde down 0.5529 7.37e-06
QHBZHVUGQROELI-SOFGYWHQSA-N <i>trans</i>-10-hydroxydec-2-enoic acid down 0.5531 9.98e-06
DAZYZDVAACSMFA-DYFSFZQGSA-N PE(15:0/20:1(11Z)) up 1.78 3.88e-05
CLPMAPXZURYSNH-CNBLIUODSA-N [(2R)-3-[2-aminoethoxy(hydroxy)phosphoryl]oxy-2-[(9Z,12Z)-octadeca-9,12-dienoyl]oxypropyl] icosanoate down 0.5606 4.63e-05
GHCZAUBVMUEKKP-XROMFQGDSA-N GUDCA down 0.5212 0.000556
XYIBRDXRRQCHLP-UHFFFAOYSA-N ethyl acetyl acetate down 0.4446 0.00243