Control_vs_COX10_Knockout

Profile details

Identifier: MTBLS1764_0001_00000002
Linked study: MTBLS1764 — Mitochondrial respiration controls neoangiogenesis during wound healing and tumour growth
Comparison: Control vs COX10 Knockout
Group A: Control group with genotype cox10fl/fl. Baseline group for comparison with COX10 knockout samples to assess the impact of gene deletion.
Group B: COX10 knockout group with genotype cox10ECKO. Key group for understanding the effects of COX10 gene deletion on endothelial cells.
Total features tested: 18
Significant features: 8
p-value threshold: 0.05
Ratio threshold (upper): 1.5
Ratio threshold (lower): 1/1.5
Date created: 2025-09-26 00:00:00

Metabolite ID (InChI Key)	Name	Direction	Ratio	p-value
ZWIADYZPOWUWEW-XVFCMESISA-N	Cytidine, 5'-(trihydrogen pyrophosphate)	up	15.35	0.00657
NBSCHQHZLSJFNQ-GASJEMHNSA-N	Glc6P	up	8.908	0.00997
GSXOAOHZAIYLCY-HSUXUTPPSA-N	D-Fructose 6-phosphate	up	7.603	0.0147
XCCTYIAWTASOJW-XVFCMESISA-N	Uridine 5'-diphosphate	up	11.41	0.0319
ZKHQWZAMYRWXGA-KQYNXXCUSA-N	Adenosine 5'-triphosphate	up	3.268	0.0304
DJJCXFVJDGTHFX-XVFCMESISA-L	uridine 5'-phosphate	up	3.329	0.0397
IERHLVCPSMICTF-XVFCMESISA-L	CMP dianion	up	2.92	0.0306
KDYFGRWQOYBRFD-UHFFFAOYSA-N	E363	down	0.4314	0.0165