{"@type":"Dataset","go_id":["https://identifiers.org/GO:0006954","https://identifiers.org/GO:0008152","https://identifiers.org/GO:0016310","https://identifiers.org/GO:0005737","https://identifiers.org/GO:0005783","https://identifiers.org/GO:0006099","https://identifiers.org/GO:0023052"],"go_kw":["inflammation","metabolism","phosphorylation","cytoplasm","endoplasmic reticulum","Krebs cycle","signaling"],"integmet_study":"MTBLS5877","mesh_chemical_id":["https://identifiers.org/mesh:C005229","https://identifiers.org/mesh:C000708109"],"mesh_chemical_pubtator_kw":["itaconate","4-OI","4-octyl itaconate"],"mesh_disease_id":["https://identifiers.org/mesh:D018805","https://identifiers.org/mesh:D007249"],"mesh_disease_pubtator_kw":["sepsis","inflammatory","inflammation"],"mesh_gene_id":["https://identifiers.org/ncbigene:730249","https://identifiers.org/ncbigene:340061"],"mesh_gene_pubtator_kw":["immune response gene 1","stimulator of interferon genes","STING","IRG1"],"source_id":"https://identifiers.org/metabolights:MTBLS5877","study_findings":"4-OI alkylates STING, inhibiting phosphorylation and inflammatory factor production.","study_observation":"4-Octyl itaconate's effect on STING signaling and inflammation.","study_summary":"4-OI inhibits inflammation via STING alkylation.","study_title_original":"4-Octyl itaconate as a metabolite derivative inhibits inflammation via alkylation of STING"}