{"@type":"Dataset","go_id":["https://identifiers.org/GO:0005829"],"go_kw":["cytosol"],"integmet_study":"MTBLS4722","mesh_chemical_id":["https://identifiers.org/mesh:C000627630","https://identifiers.org/mesh:D007656","https://identifiers.org/mesh:D005609","https://identifiers.org/mesh:D009249","https://identifiers.org/mesh:D008274","https://identifiers.org/mesh:C034219"],"mesh_chemical_pubtator_kw":["AG-120","alphaKG","alpha-ketoglutarate","free radicals","NADPH","magnesium","ivosidenib","isocitrate"],"mesh_disease_id":["https://identifiers.org/mesh:D010190","https://identifiers.org/mesh:D009369"],"mesh_disease_pubtator_kw":["pancreatic tumors","pancreatic cancer","tumor","cancer"],"mesh_gene_id":["https://identifiers.org/ncbigene:3417"],"mesh_gene_pubtator_kw":["IDH1"],"source_id":"https://identifiers.org/metabolights:MTBLS4722","study_findings":"Allosteric IDH1 inhibitors are effective under low magnesium, inhibiting tumor growth.","study_observation":"Nutrient-deprived tumor microenvironment in pancreatic cancer cells.","study_summary":"Pancreatic tumors sensitive to IDH1 inhibitors.","study_title_original":"Limited nutrient availability in the tumor microenvironment renders pancreatic tumors sensitive to allosteric IDH1 inhibitors"}