{"@type":"Dataset","integmet_study":"MTBLS1973","mesh_chemical_id":["https://identifiers.org/mesh:C019417","https://identifiers.org/mesh:D019301","https://identifiers.org/mesh:D008055","https://identifiers.org/mesh:D005229","https://identifiers.org/mesh:D010743"],"mesh_chemical_pubtator_kw":["D-2HG","oleic acid","lipid","MUFA","lipids","phospholipids","monounsaturated fatty acids"],"mesh_disease_id":["https://identifiers.org/mesh:D009369","https://identifiers.org/mesh:D005910"],"mesh_disease_pubtator_kw":["tumors","glioma","gliomas","tumor"],"mesh_gene_id":["https://identifiers.org/ncbigene:6319","https://identifiers.org/ncbigene:3417"],"mesh_gene_pubtator_kw":["stearyl-CoA desaturase","SCD","IDH1","IDH1WT"],"source_id":"https://identifiers.org/metabolights:MTBLS1973","study_findings":"IDH1 mutation causes organelle defects via SCD overexpression; oleic acid induces apoptosis in IDH1mut cells.","study_observation":"Monounsaturated to polyunsaturated lipid imbalances in organelles due to IDH mutation.","study_summary":"IDH1 mutations affect organelle morphology via lipid imbalance.","study_title_original":"IDH1 Mutations Induce Organelle Defects Via Dysregulated Phospholipids (CSHNeg)"}