{"@type":"Dataset","go_id":["https://identifiers.org/GO:0009315","https://identifiers.org/GO:0004180"],"go_kw":["drug resistance","carboxypeptidase activity"],"integmet_study":"MTBLS1474","mesh_chemical_id":["https://identifiers.org/mesh:D002264","https://identifiers.org/mesh:C000625879"],"mesh_chemical_pubtator_kw":["carboxylic acid","AN11736"],"mesh_disease_id":["https://identifiers.org/mesh:D014353","https://identifiers.org/mesh:D004194"],"mesh_disease_pubtator_kw":["nagana","Livestock diseases"],"ncbi_taxonomy_id":["https://identifiers.org/taxonomy:5692","https://identifiers.org/taxonomy:5691"],"ncbi_taxonomy_pubtator_kw":["Trypanosoma congolense","T. brucei","T. congolense"],"source_id":"https://identifiers.org/metabolights:MTBLS1474","study_findings":"CBP loss-of-function causes resistance; re-expression restores susceptibility.","study_observation":"Trypanocidal benzoxaboroles activated by trypanosome serine carboxypeptidases.","study_summary":"Benzoxaboroles are peptidase-activated prodrugs against trypanosomes.","study_title_original":"Veterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs (T. brucei assay)"}