{"chebi_id":"38940","chebi_name":"sunitinib","chebi_synonyms":["N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide","Sutent","SU-11248","Sunitinib","sunitinibum"],"diffprof_id_observed":["MTBLS2262_0001_00000008","MTBLS2406_0001_00000009","MTBLS3750_0001_00000006","MTBLS3950_0001_00000001","MTBLS4820_0002_00000001","MTBLS4967_0001_00000003","MTBLS4980_0001_00000006","MTBLS5132_0002_00000014","MTBLS5148_0002_00000014","MTBLS5195_0002_00000001","MTBLS5828_0001_00000001","MTBLS5943_0001_00000001"],"diffprof_id_var_observed":["MTBLS3750_0001_00000006","MTBLS3950_0001_00000001","MTBLS4820_0002_00000001","MTBLS5828_0001_00000001"],"inchikey":"WINHZLLDWRZWRT-ATVHPVEESA-N","inn_name":"sunitinibum","iupac_name":"<em>N</em>-[2-(diethylamino)ethyl]-5-[(<i>Z</i>)-(5-fluoro-2-oxo-1,2-dihydro-3<em>H</em>-indol-3-ylidene)methyl]-2,4-dimethyl-1<em>H</em>-pyrrole-3-carboxamide","num_study_observed":12,"reactome_ids":["R-HSA-1169410","R-HSA-1280215","R-HSA-1433557","R-HSA-162582","R-HSA-1643685","R-HSA-168256","R-HSA-186797","R-HSA-5663202","R-HSA-9006934","R-HSA-913531","R-HSA-9607240","R-HSA-9669921","R-HSA-9669934","R-HSA-9669937","R-HSA-9669938","R-HSA-9671555","R-HSA-9674401","R-HSA-9674415","R-HSA-9674428","R-HSA-9682385","R-HSA-9702506","R-HSA-9702509","R-HSA-9702632","R-HSA-9833482"],"reactome_names":["Antiviral mechanism by IFN-stimulated genes","Cytokine Signaling in Immune system","Signaling by SCF-KIT","Signal Transduction","Disease","Immune System","Signaling by PDGF","Diseases of signal transduction by growth factor receptors and second messengers","Signaling by Receptor Tyrosine Kinases","Interferon Signaling","FLT3 Signaling","KIT mutants bind TKIs","Sunitinib-resistant KIT mutants","Drug resistance of KIT mutants","Signaling by KIT in disease","Signaling by PDGFR in disease","Sunitinib-resistant PDGFR mutants","Drug resistance of PDGFR mutants","PDGFR mutants bind TKIs","FLT3 signaling in disease","Drug resistance of FLT3 mutants","FLT3 mutants bind TKIs","sunitinib-resistant FLT3 mutants","PKR-mediated signaling"],"study_id_observed":["MTBLS2262","MTBLS2406","MTBLS3750","MTBLS3950","MTBLS4820","MTBLS4967","MTBLS4980","MTBLS5132","MTBLS5148","MTBLS5195","MTBLS5828","MTBLS5943"],"study_id_var_observed":["MTBLS3750","MTBLS3950","MTBLS4820","MTBLS5828"],"synonym_name":"SU-11248"}
