{"chebi_id":"456215","chebi_name":"adenosine 5'-monophosphate(2\u2212)","chebi_synonyms":["AMP dianion","AMP","Adenosine-5-monophosphate dianion","Adenosine-5-monophosphate(2\u2212)","5'-O-phosphonatoadenosine","AMP(2\u2212)"],"diffprof_id_observed":["MTBLS1390_0001_00000004","MTBLS1390_0002_00000004","MTBLS1490_0001_00000002","MTBLS1764_0001_00000002","MTBLS181_0001_00000002","MTBLS4176_0001_00000001"],"diffprof_id_var_observed":["MTBLS1390_0001_00000004","MTBLS1390_0002_00000004","MTBLS181_0001_00000002","MTBLS4176_0001_00000001"],"inchikey":"UDMBCSSLTHHNCD-KQYNXXCUSA-L","inn_name":"","iupac_name":"5'-<em>O</em>-phosphonatoadenosine","num_study_observed":5,"reactome_ids":["R-HSA-109582","R-HSA-109703","R-HSA-109704","R-HSA-111885","R-HSA-111933","R-HSA-111957","R-HSA-111996","R-HSA-111997","R-HSA-112040","R-HSA-112043","R-HSA-112399","R-HSA-1169408","R-HSA-1169410","R-HSA-1266738","R-HSA-1280215","R-HSA-1280218","R-HSA-1428517","R-HSA-1430728","R-HSA-1445148","R-HSA-1489509","R-HSA-156580","R-HSA-156584","R-HSA-156587","R-HSA-157579","R-HSA-15869","R-HSA-1592230","R-HSA-159418","R-HSA-159424","R-HSA-162582","R-HSA-1632852","R-HSA-163680","R-HSA-163685","R-HSA-163841","R-HSA-1640170","R-HSA-1643685","R-HSA-165159","R-HSA-165160","R-HSA-168249","R-HSA-168256","R-HSA-174414","R-HSA-174417","R-HSA-174437","R-HSA-177128","R-HSA-177135","R-HSA-177162","R-HSA-180024","R-HSA-180786","R-HSA-1852241","R-HSA-192105","R-HSA-193368","R-HSA-193775","R-HSA-194068","R-HSA-196780","R-HSA-196783","R-HSA-196807","R-HSA-196819","R-HSA-196843","R-HSA-196849","R-HSA-196854","R-HSA-199220","R-HSA-199991","R-HSA-2046104","R-HSA-2046105","R-HSA-2046106","R-HSA-211859","R-HSA-211945","R-HSA-212436","R-HSA-2151209","R-HSA-2161522","R-HSA-2161541","R-HSA-2393930","R-HSA-2404192","R-HSA-2408522","R-HSA-2408557","R-HSA-2428924","R-HSA-2428928","R-HSA-2454202","R-HSA-2871837","R-HSA-2990846","R-HSA-3065676","R-HSA-3215018","R-HSA-3700989","R-HSA-372790","R-HSA-379716","R-HSA-379724","R-HSA-379726","R-HSA-380972","R-HSA-388396","R-HSA-388841","R-HSA-389599","R-HSA-389948","R-HSA-390247","R-HSA-390918","R-HSA-392499","R-HSA-400451","R-HSA-418555","R-HSA-418594","R-HSA-422356","R-HSA-429914","R-HSA-429947","R-HSA-429958","R-HSA-430039","R-HSA-434313","R-HSA-499943","R-HSA-5358493","R-HSA-5358508","R-HSA-5358565","R-HSA-5358606","R-HSA-556833","R-HSA-5607764","R-HSA-5621481","R-HSA-5628897","R-HSA-5633007","R-HSA-5653656","R-HSA-5663205","R-HSA-597592","R-HSA-611105","R-HSA-6782315","R-HSA-6784531","R-HSA-6804756","R-HSA-69166","R-HSA-69183","R-HSA-69186","R-HSA-69190","R-HSA-69239","R-HSA-69242","R-HSA-69278","R-HSA-69306","R-HSA-70171","R-HSA-70221","R-HSA-70263","R-HSA-70326","R-HSA-70635","R-HSA-71291","R-HSA-71336","R-HSA-71384","R-HSA-71387","R-HSA-72306","R-HSA-72766","R-HSA-73776","R-HSA-73817","R-HSA-73843","R-HSA-73857","R-HSA-73886","R-HSA-73894","R-HSA-74160","R-HSA-74182","R-HSA-74217","R-HSA-74259","R-HSA-74751","R-HSA-74752","R-HSA-75105","R-HSA-75876","R-HSA-76042","R-HSA-77111","R-HSA-77286","R-HSA-77289","R-HSA-77352","R-HSA-8850843","R-HSA-8852135","R-HSA-8866652","R-HSA-8951664","R-HSA-8953854","R-HSA-8953897","R-HSA-8956319","R-HSA-8956320","R-HSA-8956321","R-HSA-8957322","R-HSA-8963693","R-HSA-8978868","R-HSA-8982491","R-HSA-8983711","R-HSA-9006925","R-HSA-9006934","R-HSA-913531","R-HSA-947581","R-HSA-9612973","R-HSA-9613354","R-HSA-9658195","R-HSA-9660826","R-HSA-9663891","R-HSA-9664424","R-HSA-9748784","R-HSA-9748787","R-HSA-9749641","R-HSA-9816359","R-HSA-9820841","R-HSA-9820952","R-HSA-9824443","R-HSA-9824446","R-HSA-983168","R-HSA-983169","R-HSA-983231","R-HSA-9833110","R-HSA-9833482","R-HSA-9855142","R-HSA-9860927","R-HSA-9860931","R-HSA-9909505","R-HSA-9909615","R-HSA-9909648","R-HSA-9913635","R-HSA-9931269"],"reactome_names":["Hemostasis","PKB-mediated events","PI3K Cascade","Opioid Signalling","Calmodulin induced events","Cam-PDE 1 activation","Ca-dependent events","CaM pathway","G-protein mediated events","PLC beta mediated events","IRS-mediated signalling","ISG15 antiviral mechanism","Antiviral mechanism by IFN-stimulated genes","Developmental Biology","Cytokine Signaling in Immune system","Adaptive Immune System","Aerobic respiration and respiratory electron transport","Metabolism","Translocation of SLC2A4 (GLUT4) to the plasma membrane","DAG and IP3 signaling","Phase II - Conjugation of compounds","Cytosolic sulfonation of small molecules","Amino Acid conjugation","Telomere Maintenance","Metabolism of nucleotides","Mitochondrial biogenesis","Recycling of bile acids and salts","Conjugation of carboxylic acids","Signal Transduction","Macroautophagy","AMPK inhibits chREBP transcriptional activation activity","Integration of energy metabolism","Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation","Cell Cycle","Disease","MTOR signalling","PDE3B signalling","Innate Immune System","Immune System","Processive synthesis on the C-strand of the telomere","Telomere C-strand (Lagging Strand) Synthesis","Removal of the Flap Intermediate from the C-strand","Conjugation of salicylate with glycine","Conjugation of benzoate with glycine","Conjugation of phenylacetate with glutamine","DARPP-32 events","Extension of Telomeres","Organelle biogenesis and maintenance","Synthesis of bile acids and bile salts","Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol","Synthesis of bile acids and bile salts via 24-hydroxycholesterol","Bile acid and bile salt metabolism","Biotin transport and metabolism","Coenzyme A biosynthesis","Nicotinate metabolism","Vitamin B1 (thiamin) metabolism","Vitamin B2 (riboflavin) metabolism","Metabolism of water-soluble vitamins and cofactors","Metabolism of vitamins and cofactors","Vitamin B5 (pantothenate) metabolism","Membrane Trafficking","alpha-linolenic (omega3) and linoleic (omega6) acid metabolism","Linoleic acid (LA) metabolism","alpha-linolenic acid (ALA) metabolism","Biological oxidations","Phase I - Functionalization of compounds","Generic Transcription Pathway","Activation of PPARGC1A (PGC-1alpha) by phosphorylation","Abacavir ADME","Abacavir metabolism","Phosphate bond hydrolysis by NUDT proteins","Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)","Selenoamino acid metabolism","Selenocysteine synthesis","IGF1R signaling cascade","IRS-related events triggered by IGF1R","Fc epsilon receptor (FCERI) signaling","FCERI mediated NF-kB activation","SUMOylation","SUMO is conjugated to E1 (UBA2:SAE1)","Processing and activation of SUMO","Transcriptional Regulation by TP53","Signaling by GPCR","Cytosolic tRNA aminoacylation","tRNA Aminoacylation","Mitochondrial tRNA aminoacylation","Energy dependent regulation of mTOR by LKB1-AMPK","GPCR downstream signalling","Regulation of T cell activation by CD28 family","Alpha-oxidation of phytanate","Co-inhibition by PD-1","Beta-oxidation of very long chain fatty acids","Peroxisomal lipid metabolism","Metabolism of proteins","Free fatty acids regulate insulin secretion","G alpha (s) signalling events","G alpha (i) signalling events","Regulation of insulin secretion","Deadenylation-dependent mRNA decay","Deadenylation of mRNA","mRNA decay by 3' to 5' exoribonuclease","mRNA decay by 5' to 3' exoribonuclease","Intracellular metabolism of fatty acids regulates insulin secretion","Interconversion of nucleotide di- and triphosphates","Synthesis of diphthamide-EEF2","Mismatch Repair","Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)","Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)","Metabolism of lipids","CLEC7A (Dectin-1) signaling","C-type lectin receptors (CLRs)","TP53 Regulates Metabolic Genes","Regulation of TP53 Activity","Vesicle-mediated transport","Infectious disease","Post-translational protein modification","Respiratory electron transport","tRNA modification in the nucleus and cytosol","tRNA processing in the nucleus","Regulation of TP53 Activity through Phosphorylation","Removal of the Flap Intermediate","Processive synthesis on the lagging strand","Lagging Strand Synthesis","DNA strand elongation","Synthesis of DNA","S Phase","Cell Cycle, Mitotic","DNA Replication","Glycolysis","Glycogen breakdown (glycogenolysis)","Gluconeogenesis","Glucose metabolism","Urea cycle","Metabolism of amino acids and derivatives","Pentose phosphate pathway","Ethanol oxidation","Metabolism of carbohydrates and carbohydrate derivatives","tRNA processing","Translation","RNA Polymerase II Promoter Escape","Purine ribonucleoside monophosphate biosynthesis","5-Phosphoribose 1-diphosphate biosynthesis","RNA Polymerase II Transcription","Chromosome Maintenance","DNA Repair","Gene expression (Transcription)","Ketone body metabolism","Purine salvage","Purine catabolism","Insulin receptor signalling cascade","Signaling by Insulin receptor","Fatty acyl-CoA biosynthesis","Synthesis of very long-chain fatty acyl-CoAs","RNA Polymerase II Transcription Initiation And Promoter Clearance","Synthesis of Ketone Bodies","mitochondrial fatty acid beta-oxidation of saturated fatty acids","Mitochondrial Fatty Acid Beta-Oxidation","Beta oxidation of butanoyl-CoA to acetyl-CoA","Phosphate bond hydrolysis by NTPDase proteins","Protein ubiquitination","Synthesis of active ubiquitin: roles of E1 and E2 enzymes","Neddylation","Metabolism of RNA","Cellular responses to stimuli","Nucleotide catabolism","Nucleotide biosynthesis","Nucleotide salvage","Metabolism of steroids","Aspartate and asparagine metabolism","Fatty acid metabolism","Glycogen metabolism","OAS antiviral response","Intracellular signaling by second messengers","Signaling by Receptor Tyrosine Kinases","Interferon Signaling","Molybdenum cofactor biosynthesis","Autophagy","Lipophagy","Leishmania infection","Purinergic signaling in leishmaniasis infection","Selective autophagy","Cell recruitment (pro-inflammatory response)","Drug ADME","Azathioprine ADME","Aspirin ADME","Maternal to zygotic transition (MZT)","M-decay: degradation of maternal mRNAs by maternally stored factors","Respiratory Syncytial Virus Infection Pathway","Parasitic Infection Pathways","Viral Infection Pathways","Antigen processing: Ubiquitination & Proteasome degradation","Class I MHC mediated antigen processing & presentation","Factors involved in megakaryocyte development and platelet production","RSV-host interactions","PKR-mediated signaling","Cellular responses to mechanical stimuli","Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells","Response of endothelial cells to shear stress","Modulation of host responses by IFN-stimulated genes","Regulation of PD-L1(CD274) Post-translational modification","Regulation of PD-L1(CD274) expression","Strand-asynchronous mitochondrial DNA replication","AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274)"],"study_id_observed":["MTBLS1390","MTBLS1490","MTBLS1764","MTBLS181","MTBLS4176"],"study_id_var_observed":["MTBLS1390","MTBLS181","MTBLS4176"],"synonym_name":"AMP dianion"}