{"chebi_id":"15367","chebi_name":"all-trans-retinoic acid","chebi_synonyms":["(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)nona-2,4,6,8-tetraenoic acid","tr\u00e9tino\u00efne","Betarretin","Avita","3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2E,4E,6E,8E-tetraenoic acid","Cordes vas","Stieva-A","Atralin","3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-enyl)nona-2,4,6,8-all-trans-tetraenoic acid","Refissa","Tri-luma","tretinoinum","(all-E)-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid","Ro 1-5488","all-trans-beta-Retinoic acid","AGN 100335","all-(E)-retinoic acid","3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexene-1-yl)-2,4,6,8-nonatetraenoic acid","beta-Retinoic acid","all-trans-vitamin A1 acid","trans-retinoic acid","Renova","Retin-A","Vesanoid","all-trans retinoic acid","tretinoin","Dermairol","Retisol-A","Veltin","Acide retinoique (French)","Biacna","vitamin A acid","retinoic acid","Altreno","Tretin M","(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid","tretino\u00edna","all-trans-tretinoin","all-trans-vitamin A acid"],"diffprof_id_observed":["MTBLS2406_0002_00000009","MTBLS2945_0002_00000003","MTBLS3056_0001_00000001","MTBLS3637_0001_00000001","MTBLS4980_0001_00000006","MTBLS5132_0001_00000014","MTBLS5148_0001_00000014","MTBLS6603_0002_00000001","MTBLS6661_0001_00000001","MTBLS6758_0001_00000002","MTBLS6927_0001_00000001"],"diffprof_id_var_observed":["MTBLS2945_0002_00000003","MTBLS4980_0001_00000006","MTBLS5132_0001_00000014","MTBLS6661_0001_00000001"],"inchikey":"SHGAZHPCJJPHSC-YCNIQYBTSA-N","inn_name":"tr\u00e9tino\u00efne","iupac_name":"(2<i>E</i>,4<i>E</i>,6<i>E</i>,8<i>E</i>)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid","num_study_observed":11,"reactome_ids":["R-HSA-1266738","R-HSA-1430728","R-HSA-162582","R-HSA-1643685","R-HSA-196854","R-HSA-200425","R-HSA-211859","R-HSA-211897","R-HSA-211916","R-HSA-211945","R-HSA-211958","R-HSA-212436","R-HSA-2187338","R-HSA-5362517","R-HSA-5365859","R-HSA-556833","R-HSA-5579015","R-HSA-5579029","R-HSA-5617472","R-HSA-5619507","R-HSA-5668914","R-HSA-6806667","R-HSA-73857","R-HSA-74160","R-HSA-8864260","R-HSA-8869496","R-HSA-8978868","R-HSA-9006931","R-HSA-9006936","R-HSA-9616222","R-HSA-9709957","R-HSA-9725554","R-HSA-9734767","R-HSA-9734779","R-HSA-975634","R-HSA-9758941","R-HSA-9761174","R-HSA-9820448","R-HSA-9830364","R-HSA-9830369","R-HSA-9839373","R-HSA-9839394","R-HSA-9937080"],"reactome_names":["Developmental Biology","Metabolism","Signal Transduction","Disease","Metabolism of vitamins and cofactors","Carnitine shuttle","Biological oxidations","Cytochrome P450 - arranged by substrate type","Vitamins","Phase I - Functionalization of compounds","Miscellaneous substrates","Generic Transcription Pathway","Visual phototransduction","Signaling by Retinoic Acid","RA biosynthesis pathway","Metabolism of lipids","Defective CYP26B1 causes RHFCA","Metabolic disorders of biological oxidation enzymes","Activation of anterior HOX genes in hindbrain development during early embryogenesis","Activation of HOX genes during differentiation","Diseases of metabolism","Metabolism of fat-soluble vitamins","RNA Polymerase II Transcription","Gene expression (Transcription)","Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors","TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation","Fatty acid metabolism","Signaling by Nuclear Receptors","Signaling by TGFB family members","Transcriptional regulation of granulopoiesis","Sensory Perception","Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin","Developmental Cell Lineages","Developmental Cell Lineages of the Integumentary System","Retinoid metabolism and transport","Gastrulation","Formation of intermediate mesoderm","Developmental Cell Lineages of the Exocrine Pancreas","Formation of the nephric duct","Kidney development","Signaling by TGFBR3","TGFBR3 expression","Developmental Lineage of Multipotent Pancreatic Progenitor Cells"],"study_id_observed":["MTBLS2406","MTBLS2945","MTBLS3056","MTBLS3637","MTBLS4980","MTBLS5132","MTBLS5148","MTBLS6603","MTBLS6661","MTBLS6758","MTBLS6927"],"study_id_var_observed":["MTBLS2945","MTBLS4980","MTBLS5132","MTBLS6661"],"synonym_name":"(2<i>E</i>,4<i>E</i>,6<i>E</i>,8<i>E</i>)-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)nona-2,4,6,8-tetraenoic acid"}