{"chebi_id":"61049","chebi_name":"tacrolimus (anhydrous)","chebi_synonyms":["tacrolimus","tacrolimus anhydrous","Prograf","(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,19-dihydroxy-3-{(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl}-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(prop-2-en-1-yl)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-3H-15,19-epoxypyrido[2,1-c][1,4]oxazacyclotricosine-1,7,20,21(4H,23H)-tetrone","(\u2212)-FK 506","FK506","FK 506","Tacrolimus","8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN"],"diffprof_id_observed":["MTBLS2406_0001_00000009","MTBLS2878_0002_00000001","MTBLS3963_0002_00000001","MTBLS5132_0002_00000014","MTBLS5148_0002_00000014","MTBLS5195_0001_00000001"],"diffprof_id_var_observed":[],"inchikey":"QJJXYPPXXYFBGM-LFZNUXCKSA-N","inn_name":"tacrolimus","iupac_name":"(3<i>S</i>,4<i>R</i>,5<i>S</i>,8<i>R</i>,9<i>E</i>,12<i>S</i>,14<i>S</i>,15<i>R</i>,16<i>S</i>,18<i>R</i>,19<i>R</i>,26a<i>S</i>)-5,19-dihydroxy-3-{(1<i>E</i>)-1-[(1<i>R</i>,3<i>R</i>,4<i>R</i>)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl}-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(prop-2-en-1-yl)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-3<em>H</em>-15,19-epoxypyrido[2,1-<em>c</em>][1,4]oxazacyclotricosine-1,7,20,21(4<em>H</em>,23<em>H</em>)-tetrone","num_study_observed":6,"reactome_ids":["R-HSA-1168372","R-HSA-1280218","R-HSA-1643685","R-HSA-168256","R-HSA-2025928","R-HSA-5663205","R-HSA-9679191","R-HSA-9679506","R-HSA-9824446","R-HSA-983705"],"reactome_names":["Downstream signaling events of B Cell Receptor (BCR)","Adaptive Immune System","Disease","Immune System","Calcineurin activates NFAT","Infectious disease","Potential therapeutics for SARS","SARS-CoV Infections","Viral Infection Pathways","Signaling by the B Cell Receptor (BCR)"],"study_id_observed":["MTBLS2406","MTBLS2878","MTBLS3963","MTBLS5132","MTBLS5148","MTBLS5195"],"study_id_var_observed":[],"synonym_name":"(\u2212)-FK 506"}