{"chebi_id":"17351","chebi_name":"linoleic acid","chebi_synonyms":["9-cis,12-cis-Octadecadienoic acid","9Z,12Z-octadecadienoic acid","(Z,Z)-9,12-octadecadienoic acid","(9Z,12Z)-octadeca-9,12-dienoic acid","cis,cis-linoleic acid","cis-\u03949,12-octadecadienoic acid","LINOLEIC ACID","Linoleic acid","(9Z,12Z)-Octadecadienoic acid","cis,cis-9,12-octadecadienoic acid","C18:2 9c, 12c \u03c96 todos cis-9,12-octadienoico","\u00e1cido linoleico","acide linol\u00e9ique","C18:2, n-6,9 all-cis","LA","linolic acid","all-cis-9,12-octadecadienoic acid","acide cis-linol\u00e9ique"],"diffprof_id_observed":["MTBLS1182_0001_00000001","MTBLS1191_0001_00000001","MTBLS1191_0002_00000001","MTBLS1196_0001_00000001","MTBLS1411_0001_00000001","MTBLS1411_0002_00000001","MTBLS1796_0001_00000001","MTBLS1847_0001_00000001","MTBLS1890_0001_00000007","MTBLS1973_0001_00000002","MTBLS1980_0001_00000001","MTBLS2015_0001_00000001","MTBLS2015_0002_00000001","MTBLS208_0001_00000006","MTBLS2279_0001_00000005","MTBLS2317_0002_00000001","MTBLS2322_0001_00000001","MTBLS2322_0002_00000001","MTBLS2324_0001_00000001","MTBLS2324_0002_00000001","MTBLS2406_0002_00000009","MTBLS2597_0001_00000001","MTBLS2737_0002_00000003","MTBLS2771_0001_00000002","MTBLS2825_0001_00000004","MTBLS2871_0001_00000009","MTBLS2945_0002_00000003","MTBLS297_0002_00000001","MTBLS3056_0002_00000001","MTBLS312_0001_00000009","MTBLS312_0003_00000009","MTBLS3233_0002_00000003","MTBLS3306_0001_00000014","MTBLS3306_0002_00000014","MTBLS3358_0001_00000001","MTBLS3540_0001_00000002","MTBLS360_0001_00000001","MTBLS3627_0001_00000007","MTBLS3637_0001_00000001","MTBLS3657_0001_00000003","MTBLS3725_0002_00000003","MTBLS3750_0002_00000006","MTBLS3769_0001_00000001","MTBLS3927_0001_00000001","MTBLS3927_0002_00000001","MTBLS3963_0001_00000001","MTBLS4099_0001_00000001","MTBLS4099_0003_00000001","MTBLS4187_0001_00000006","MTBLS4387_0003_00000001","MTBLS4469_0001_00000001","MTBLS4568_0001_00000005","MTBLS4579_0001_00000001","MTBLS45_0001_00000001","MTBLS4893_0001_00000003","MTBLS4893_0002_00000003","MTBLS4894_0001_00000003","MTBLS4967_0002_00000003","MTBLS4980_0001_00000006","MTBLS5195_0002_00000001","MTBLS519_0001_00000001","MTBLS5297_0001_00000005","MTBLS5335_0002_00000003","MTBLS548_0001_00000001","MTBLS548_0002_00000001","MTBLS5828_0001_00000001","MTBLS5943_0001_00000001","MTBLS627_0001_00000001","MTBLS6603_0001_00000001","MTBLS6890_0001_00000001","MTBLS6982_0001_00000001","MTBLS726_0001_00000001","MTBLS7584_0001_00000003","MTBLS7711_0001_00000003","MTBLS7713_0001_00000003","MTBLS809_0001_00000001","MTBLS893_0001_00000001"],"diffprof_id_var_observed":["MTBLS1847_0001_00000001","MTBLS2015_0001_00000001","MTBLS2322_0002_00000001","MTBLS2771_0001_00000002","MTBLS2945_0002_00000003","MTBLS297_0002_00000001","MTBLS312_0001_00000009","MTBLS4387_0003_00000001","MTBLS4893_0001_00000003","MTBLS4894_0001_00000003","MTBLS4980_0001_00000006","MTBLS519_0001_00000001","MTBLS5297_0001_00000005","MTBLS5828_0001_00000001","MTBLS6982_0001_00000001","MTBLS809_0001_00000001"],"inchikey":"OYHQOLUKZRVURQ-HZJYTTRNSA-N","inn_name":"","iupac_name":"(9<i>Z</i>,12<i>Z</i>)-octadeca-9,12-dienoic acid","num_study_observed":66,"reactome_ids":["R-HSA-1266738","R-HSA-1368108","R-HSA-1430728","R-HSA-1592230","R-HSA-1643685","R-HSA-1655829","R-HSA-1852241","R-HSA-196854","R-HSA-1989781","R-HSA-2046104","R-HSA-2046105","R-HSA-2151201","R-HSA-2187338","R-HSA-2262752","R-HSA-2426168","R-HSA-2453902","R-HSA-381340","R-HSA-382551","R-HSA-400206","R-HSA-425397","R-HSA-425407","R-HSA-556833","R-HSA-5619102","R-HSA-5619108","R-HSA-5619115","R-HSA-6806667","R-HSA-804914","R-HSA-8953897","R-HSA-8957322","R-HSA-8978868","R-HSA-9707564","R-HSA-9707616","R-HSA-9709957","R-HSA-9711123","R-HSA-975634","R-HSA-9843745","R-HSA-9909396","R-HSA-9931509","R-HSA-9933387"],"reactome_names":["Developmental Biology","BMAL1:CLOCK,NPAS2 activates circadian expression","Metabolism","Mitochondrial biogenesis","Disease","Regulation of cholesterol biosynthesis by SREBP (SREBF)","Organelle biogenesis and maintenance","Metabolism of vitamins and cofactors","PPARA activates gene expression","alpha-linolenic (omega3) and linoleic (omega6) acid metabolism","Linoleic acid (LA) metabolism","Transcriptional activation of mitochondrial biogenesis","Visual phototransduction","Cellular responses to stress","Activation of gene expression by SREBF (SREBP)","The canonical retinoid cycle in rods (twilight vision)","Transcriptional regulation of white adipocyte differentiation","Transport of small molecules","Regulation of lipid metabolism by PPARalpha","Transport of vitamins, nucleosides, and related molecules","SLC-mediated transmembrane transport","Metabolism of lipids","SLC transporter disorders","Defective SLC27A4 causes ichthyosis prematurity syndrome (IPS)","Disorders of transmembrane transporters","Metabolism of fat-soluble vitamins","Transport of fatty acids","Cellular responses to stimuli","Metabolism of steroids","Fatty acid metabolism","Cytoprotection by HMOX1","Heme signaling","Sensory Perception","Cellular response to chemical stress","Retinoid metabolism and transport","Adipogenesis","Circadian clock","Expression of BMAL (ARNTL), CLOCK, and NPAS2","RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression"],"study_id_observed":["MTBLS1182","MTBLS1191","MTBLS1196","MTBLS1411","MTBLS1796","MTBLS1847","MTBLS1890","MTBLS1973","MTBLS1980","MTBLS2015","MTBLS208","MTBLS2279","MTBLS2317","MTBLS2322","MTBLS2324","MTBLS2406","MTBLS2597","MTBLS2737","MTBLS2771","MTBLS2825","MTBLS2871","MTBLS2945","MTBLS297","MTBLS3056","MTBLS312","MTBLS3233","MTBLS3306","MTBLS3358","MTBLS3540","MTBLS360","MTBLS3627","MTBLS3637","MTBLS3657","MTBLS3725","MTBLS3750","MTBLS3769","MTBLS3927","MTBLS3963","MTBLS4099","MTBLS4187","MTBLS4387","MTBLS4469","MTBLS45","MTBLS4568","MTBLS4579","MTBLS4893","MTBLS4894","MTBLS4967","MTBLS4980","MTBLS519","MTBLS5195","MTBLS5297","MTBLS5335","MTBLS548","MTBLS5828","MTBLS5943","MTBLS627","MTBLS6603","MTBLS6890","MTBLS6982","MTBLS726","MTBLS7584","MTBLS7711","MTBLS7713","MTBLS809","MTBLS893"],"study_id_var_observed":["MTBLS1847","MTBLS2015","MTBLS2322","MTBLS2771","MTBLS2945","MTBLS297","MTBLS312","MTBLS4387","MTBLS4893","MTBLS4894","MTBLS4980","MTBLS519","MTBLS5297","MTBLS5828","MTBLS6982","MTBLS809"],"synonym_name":"Linoleic acid"}