{"chebi_id":"16335","chebi_name":"adenosine","chebi_synonyms":["Adenocor","Adenoscan","Adenosin","9-\u03b2-D-ribofuranosyl-9H-purin-6-amine","Ado","ADENOSINE","6-Amino-9-beta-D-ribofuranosyl-9H-purine","Ade-Rib","9-beta-D-Ribofuranosidoadenine","(2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol","Adenosine","\u03b2-D-adenosine","9-beta-D-Ribofuranosyl-9H-purin-6-amine","Adenocard","adenine riboside","9-\u03b2-D-ribofuranosyladenine"],"diffprof_id_observed":["MTBLS1122_0001_00000017","MTBLS1182_0001_00000001","MTBLS1188_0001_00000002","MTBLS1188_0002_00000002","MTBLS1191_0001_00000001","MTBLS125_0001_00000005","MTBLS125_0002_00000005","MTBLS127_0002_00000027","MTBLS127_0003_00000002","MTBLS1411_0002_00000001","MTBLS1550_0001_00000001","MTBLS159_0001_00000001","MTBLS159_0002_00000001","MTBLS159_0003_00000001","MTBLS159_0004_00000001","MTBLS1792_0001_00000018","MTBLS181_0001_00000002","MTBLS1858_0001_00000001","MTBLS1980_0001_00000001","MTBLS2015_0001_00000001","MTBLS2015_0002_00000001","MTBLS208_0001_00000006","MTBLS2108_0002_00000001","MTBLS2145_0001_00000029","MTBLS2145_0002_00000029","MTBLS2145_0003_00000029","MTBLS2145_0006_00000029","MTBLS2279_0001_00000005","MTBLS2322_0002_00000001","MTBLS2323_0001_00000001","MTBLS2324_0001_00000001","MTBLS2324_0002_00000001","MTBLS2384_0002_00000005","MTBLS23_0001_00000001","MTBLS2406_0001_00000009","MTBLS2559_0001_00000001","MTBLS2771_0001_00000002","MTBLS2782_0002_00000009","MTBLS2840_0002_00000026","MTBLS293_0001_00000005","MTBLS293_0002_00000005","MTBLS2945_0002_00000003","MTBLS295_0001_00000001","MTBLS295_0002_00000001","MTBLS297_0001_00000001","MTBLS3003_0002_00000001","MTBLS303_0002_00000006","MTBLS3056_0001_00000001","MTBLS312_0002_00000009","MTBLS316_0002_00000009","MTBLS3306_0001_00000014","MTBLS3306_0002_00000014","MTBLS3318_0001_00000001","MTBLS3358_0001_00000001","MTBLS338_0001_00000001","MTBLS3518_0001_00000001","MTBLS353_0001_00000001","MTBLS3540_0001_00000002","MTBLS360_0001_00000001","MTBLS360_0002_00000001","MTBLS3627_0001_00000007","MTBLS3637_0002_00000001","MTBLS3657_0001_00000003","MTBLS3725_0002_00000003","MTBLS3750_0001_00000006","MTBLS376_0001_00000001","MTBLS376_0003_00000001","MTBLS37_0001_00000005","MTBLS3927_0001_00000001","MTBLS3927_0002_00000001","MTBLS3963_0002_00000001","MTBLS403_0001_00000008","MTBLS4046_0002_00000014","MTBLS4099_0003_00000001","MTBLS4249_0002_00000001","MTBLS437_0001_00000001","MTBLS43_0001_00000003","MTBLS4463_0001_00000001","MTBLS4469_0001_00000001","MTBLS44_0001_00000003","MTBLS4579_0001_00000001","MTBLS4722_0001_00000001","MTBLS4820_0002_00000001","MTBLS4893_0001_00000003","MTBLS4893_0003_00000003","MTBLS4967_0002_00000003","MTBLS4980_0002_00000006","MTBLS5132_0002_00000014","MTBLS5148_0002_00000014","MTBLS5195_0002_00000001","MTBLS5297_0002_00000005","MTBLS5335_0002_00000003","MTBLS533_0001_00000001","MTBLS545_0001_00000001","MTBLS5462_0001_00000002","MTBLS5462_0001_00000050","MTBLS5462_0001_00000089","MTBLS5462_0001_00000119","MTBLS5462_0001_00000140","MTBLS5462_0001_00000152","MTBLS549_0002_00000006","MTBLS54_0001_00000003","MTBLS5828_0002_00000001","MTBLS5877_0001_00000002","MTBLS5971_0001_00000001","MTBLS5_0001_00000001","MTBLS629_0002_00000001","MTBLS6337_0001_00000002","MTBLS6402_0001_00000001","MTBLS6402_0002_00000001","MTBLS6516_0002_00000002","MTBLS6603_0001_00000001","MTBLS6603_0002_00000001","MTBLS6661_0002_00000001","MTBLS67_0002_00000003","MTBLS686_0001_00000001","MTBLS6886_0003_00000001","MTBLS6890_0002_00000001","MTBLS6927_0001_00000001","MTBLS726_0001_00000001","MTBLS745_0001_00000002","MTBLS7584_0001_00000003","MTBLS7584_0003_00000003","MTBLS7711_0001_00000003","MTBLS7713_0001_00000003","MTBLS795_0001_00000001","MTBLS873_0001_00000002","MTBLS87_0001_00000001","MTBLS87_0003_00000001","MTBLS87_0005_00000001","MTBLS883_0001_00000014","MTBLS88_0002_00000001","MTBLS88_0004_00000001"],"diffprof_id_var_observed":["MTBLS1188_0001_00000002","MTBLS1188_0002_00000002","MTBLS1411_0002_00000001","MTBLS1550_0001_00000001","MTBLS1858_0001_00000001","MTBLS1980_0001_00000001","MTBLS2015_0002_00000001","MTBLS2108_0002_00000001","MTBLS2145_0006_00000029","MTBLS2322_0002_00000001","MTBLS2323_0001_00000001","MTBLS2324_0002_00000001","MTBLS23_0001_00000001","MTBLS2840_0002_00000026","MTBLS297_0001_00000001","MTBLS3056_0001_00000001","MTBLS316_0002_00000009","MTBLS3318_0001_00000001","MTBLS3358_0001_00000001","MTBLS338_0001_00000001","MTBLS3518_0001_00000001","MTBLS353_0001_00000001","MTBLS3657_0001_00000003","MTBLS403_0001_00000008","MTBLS4099_0003_00000001","MTBLS437_0001_00000001","MTBLS4463_0001_00000001","MTBLS4722_0001_00000001","MTBLS5335_0002_00000003","MTBLS5462_0001_00000152","MTBLS54_0001_00000003","MTBLS5828_0002_00000001","MTBLS5971_0001_00000001","MTBLS5_0001_00000001","MTBLS6603_0001_00000001","MTBLS6603_0002_00000001","MTBLS6661_0002_00000001","MTBLS686_0001_00000001","MTBLS7584_0003_00000003","MTBLS7713_0001_00000003","MTBLS87_0001_00000001","MTBLS87_0003_00000001","MTBLS87_0005_00000001","MTBLS88_0002_00000001","MTBLS88_0004_00000001"],"inchikey":"OIRDTQYFTABQOQ-KQYNXXCUSA-N","inn_name":"","iupac_name":"adenosine","num_study_observed":104,"reactome_ids":["R-HSA-1430728","R-HSA-156580","R-HSA-156581","R-HSA-15869","R-HSA-1614635","R-HSA-162582","R-HSA-1643685","R-HSA-166520","R-HSA-187015","R-HSA-187024","R-HSA-187037","R-HSA-211859","R-HSA-2161522","R-HSA-2161541","R-HSA-2408508","R-HSA-2408522","R-HSA-372790","R-HSA-373076","R-HSA-382551","R-HSA-388396","R-HSA-392499","R-HSA-417973","R-HSA-418038","R-HSA-418555","R-HSA-418594","R-HSA-425397","R-HSA-425407","R-HSA-500792","R-HSA-5619063","R-HSA-5619102","R-HSA-5619115","R-HSA-5663205","R-HSA-5668914","R-HSA-5683826","R-HSA-71291","R-HSA-73894","R-HSA-73942","R-HSA-73943","R-HSA-74217","R-HSA-74259","R-HSA-83936","R-HSA-8956319","R-HSA-8956321","R-HSA-9006934","R-HSA-9658195","R-HSA-9660821","R-HSA-9662851","R-HSA-9664433","R-HSA-9734207","R-HSA-9734735","R-HSA-9735804","R-HSA-9748784","R-HSA-9824443"],"reactome_names":["Metabolism","Phase II - Conjugation of compounds","Methylation","Metabolism of nucleotides","Sulfur amino acid metabolism","Signal Transduction","Disease","Signaling by NTRKs","Activation of TRKA receptors","NGF-independant TRKA activation","Signaling by NTRK1 (TRKA)","Biological oxidations","Abacavir ADME","Abacavir metabolism","Metabolism of ingested SeMet, Sec, MeSec into H2Se","Selenoamino acid metabolism","Signaling by GPCR","Class A/1 (Rhodopsin-like receptors)","Transport of small molecules","GPCR downstream signalling","Metabolism of proteins","Adenosine P1 receptors","Nucleotide-like (purinergic) receptors","G alpha (s) signalling events","G alpha (i) signalling events","Transport of vitamins, nucleosides, and related molecules","SLC-mediated transmembrane transport","GPCR ligand binding","Defective SLC29A3 causes histiocytosis-lymphadenopathy plus syndrome (HLAS)","SLC transporter disorders","Disorders of transmembrane transporters","Infectious disease","Diseases of metabolism","Surfactant metabolism","Metabolism of amino acids and derivatives","DNA Repair","DNA Damage Reversal","Reversal of alkylation damage by DNA dioxygenases","Purine salvage","Purine catabolism","Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane","Nucleotide catabolism","Nucleotide salvage","Signaling by Receptor Tyrosine Kinases","Leishmania infection","ADORA2B mediated anti-inflammatory cytokines production","Anti-inflammatory response favouring Leishmania parasite infection","Leishmania parasite growth and survival","Nucleotide salvage defects","Defective ADA disrupts (deoxy)adenosine deamination","Diseases of nucleotide metabolism","Drug ADME","Parasitic Infection Pathways"],"study_id_observed":["MTBLS1122","MTBLS1182","MTBLS1188","MTBLS1191","MTBLS125","MTBLS127","MTBLS1411","MTBLS1550","MTBLS159","MTBLS1792","MTBLS181","MTBLS1858","MTBLS1980","MTBLS2015","MTBLS208","MTBLS2108","MTBLS2145","MTBLS2279","MTBLS23","MTBLS2322","MTBLS2323","MTBLS2324","MTBLS2384","MTBLS2406","MTBLS2559","MTBLS2771","MTBLS2782","MTBLS2840","MTBLS293","MTBLS2945","MTBLS295","MTBLS297","MTBLS3003","MTBLS303","MTBLS3056","MTBLS312","MTBLS316","MTBLS3306","MTBLS3318","MTBLS3358","MTBLS338","MTBLS3518","MTBLS353","MTBLS3540","MTBLS360","MTBLS3627","MTBLS3637","MTBLS3657","MTBLS37","MTBLS3725","MTBLS3750","MTBLS376","MTBLS3927","MTBLS3963","MTBLS403","MTBLS4046","MTBLS4099","MTBLS4249","MTBLS43","MTBLS437","MTBLS44","MTBLS4463","MTBLS4469","MTBLS4579","MTBLS4722","MTBLS4820","MTBLS4893","MTBLS4967","MTBLS4980","MTBLS5","MTBLS5132","MTBLS5148","MTBLS5195","MTBLS5297","MTBLS533","MTBLS5335","MTBLS54","MTBLS545","MTBLS5462","MTBLS549","MTBLS5828","MTBLS5877","MTBLS5971","MTBLS629","MTBLS6337","MTBLS6402","MTBLS6516","MTBLS6603","MTBLS6661","MTBLS67","MTBLS686","MTBLS6886","MTBLS6890","MTBLS6927","MTBLS726","MTBLS745","MTBLS7584","MTBLS7711","MTBLS7713","MTBLS795","MTBLS87","MTBLS873","MTBLS88","MTBLS883"],"study_id_var_observed":["MTBLS1188","MTBLS1411","MTBLS1550","MTBLS1858","MTBLS1980","MTBLS2015","MTBLS2108","MTBLS2145","MTBLS23","MTBLS2322","MTBLS2323","MTBLS2324","MTBLS2840","MTBLS297","MTBLS3056","MTBLS316","MTBLS3318","MTBLS3358","MTBLS338","MTBLS3518","MTBLS353","MTBLS3657","MTBLS403","MTBLS4099","MTBLS437","MTBLS4463","MTBLS4722","MTBLS5","MTBLS5335","MTBLS54","MTBLS5462","MTBLS5828","MTBLS5971","MTBLS6603","MTBLS6661","MTBLS686","MTBLS7584","MTBLS7713","MTBLS87","MTBLS88"],"synonym_name":"Adenosin"}