{"chebi_id":"45783","chebi_name":"imatinib","chebi_synonyms":["\u03b1-(4-methyl-1-piperazinyl)-3'-((4-(3-pyridyl)-2-pyrimidinyl)amino)-p-toluidide","STI 571","4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE","4-[(4-methylpiperazin-1-yl)methyl]-N-{4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl}benzamide"],"diffprof_id_observed":["MTBLS2406_0002_00000009","MTBLS3750_0001_00000006"],"diffprof_id_var_observed":["MTBLS2406_0002_00000009","MTBLS3750_0001_00000006"],"inchikey":"KTUFNOKKBVMGRW-UHFFFAOYSA-N","inn_name":"imatinib","iupac_name":"4-[(4-methylpiperazin-1-yl)methyl]-<em>N</em>-{4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl}benzamide","num_study_observed":2,"reactome_ids":["R-HSA-1433557","R-HSA-162582","R-HSA-1643685","R-HSA-186797","R-HSA-382551","R-HSA-382556","R-HSA-5663202","R-HSA-9006934","R-HSA-9669917","R-HSA-9669921","R-HSA-9669937","R-HSA-9669938","R-HSA-9671555","R-HSA-9674396","R-HSA-9674415","R-HSA-9674428","R-HSA-9748784","R-HSA-9757110"],"reactome_names":["Signaling by SCF-KIT","Signal Transduction","Disease","Signaling by PDGF","Transport of small molecules","ABC-family proteins mediated transport","Diseases of signal transduction by growth factor receptors and second messengers","Signaling by Receptor Tyrosine Kinases","Imatinib-resistant KIT mutants","KIT mutants bind TKIs","Drug resistance of KIT mutants","Signaling by KIT in disease","Signaling by PDGFR in disease","Imatinib-resistant PDGFR mutants","Drug resistance of PDGFR mutants","PDGFR mutants bind TKIs","Drug ADME","Prednisone ADME"],"study_id_observed":["MTBLS2406","MTBLS3750"],"study_id_var_observed":["MTBLS2406","MTBLS3750"],"synonym_name":"STI 571"}