{"chebi_id":"64310","chebi_name":"crizotinib","chebi_synonyms":["PF 2341066","PF-2341066","3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]pyridin-2-amine","crizotinibum","(R)-crizotinib"],"diffprof_id_observed":["MTBLS3950_0001_00000001","MTBLS5828_0001_00000001"],"diffprof_id_var_observed":["MTBLS3950_0001_00000001"],"inchikey":"KTEIFNKAUNYNJU-GFCCVEGCSA-N","inn_name":"crizotinib","iupac_name":"3-[(1<i>R</i>)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)-1<em>H</em>-pyrazol-4-yl]pyridin-2-amine","num_study_observed":2,"reactome_ids":["R-HSA-162582","R-HSA-1643685","R-HSA-201556","R-HSA-5663202","R-HSA-6806834","R-HSA-6806942","R-HSA-6807004","R-HSA-9006934","R-HSA-9700206","R-HSA-9700645","R-HSA-9700649","R-HSA-9717326","R-HSA-9725370","R-HSA-9725371","R-HSA-9734091"],"reactome_names":["Signal Transduction","Disease","Signaling by ALK","Diseases of signal transduction by growth factor receptors and second messengers","Signaling by MET","MET Receptor Activation","Negative regulation of MET activity","Signaling by Receptor Tyrosine Kinases","Signaling by ALK in cancer","ALK mutants bind TKIs","Drug resistance of ALK mutants","crizotinib-resistant ALK mutants","Signaling by ALK fusions and activated point mutants","Nuclear events stimulated by ALK signaling in cancer","Drug-mediated inhibition of MET activation"],"study_id_observed":["MTBLS3950","MTBLS5828"],"study_id_var_observed":["MTBLS3950"],"synonym_name":"PF 2341066"}