{"chebi_id":"16113","chebi_name":"cholesterol","chebi_synonyms":["Cholesterol","(3\u03b2,14\u03b2,17\u03b1)-cholest-5-en-3-ol","CHOLESTEROL","cholest-5-en-3\u03b2-ol","Cholesterin","Cholest-5-en-3beta-ol"],"diffprof_id_observed":["MTBLS106_0001_00000001","MTBLS1196_0001_00000001","MTBLS159_0001_00000001","MTBLS159_0002_00000001","MTBLS159_0003_00000001","MTBLS159_0004_00000001","MTBLS1830_0001_00000001","MTBLS1980_0001_00000001","MTBLS208_0001_00000006","MTBLS2145_0002_00000029","MTBLS2145_0005_00000029","MTBLS2279_0001_00000005","MTBLS2322_0001_00000001","MTBLS2324_0001_00000001","MTBLS2406_0002_00000009","MTBLS2457_0001_00000001","MTBLS312_0001_00000009","MTBLS3750_0002_00000006","MTBLS3963_0002_00000001","MTBLS4013_0001_00000010","MTBLS4099_0001_00000001","MTBLS40_0001_00000001","MTBLS437_0001_00000001","MTBLS4579_0001_00000001","MTBLS45_0001_00000001","MTBLS4893_0001_00000003","MTBLS4894_0001_00000003","MTBLS4932_0001_00000005","MTBLS522_0001_00000002","MTBLS533_0001_00000001","MTBLS545_0001_00000001","MTBLS545_0002_00000001","MTBLS545_0003_00000001","MTBLS5877_0001_00000002","MTBLS5971_0001_00000001","MTBLS600_0001_00000001","MTBLS686_0001_00000001","MTBLS6886_0004_00000001","MTBLS726_0001_00000001","MTBLS739_0001_00000001","MTBLS7584_0001_00000003","MTBLS789_0001_00000001","MTBLS795_0001_00000001"],"diffprof_id_var_observed":["MTBLS1830_0001_00000001","MTBLS1980_0001_00000001","MTBLS2145_0005_00000029","MTBLS2322_0001_00000001","MTBLS2324_0001_00000001","MTBLS4013_0001_00000010","MTBLS437_0001_00000001","MTBLS739_0001_00000001"],"inchikey":"HVYWMOMLDIMFJA-DPAQBDIFSA-N","inn_name":"","iupac_name":"cholest-5-en-3\u03b2-ol","num_study_observed":37,"reactome_ids":["R-HSA-109582","R-HSA-1266738","R-HSA-1369062","R-HSA-1430728","R-HSA-156580","R-HSA-156584","R-HSA-162582","R-HSA-163560","R-HSA-1643685","R-HSA-1655829","R-HSA-168249","R-HSA-168256","R-HSA-168898","R-HSA-174824","R-HSA-191273","R-HSA-192105","R-HSA-192456","R-HSA-193368","R-HSA-193775","R-HSA-193807","R-HSA-194068","R-HSA-196071","R-HSA-196108","R-HSA-196854","R-HSA-199991","R-HSA-202733","R-HSA-211859","R-HSA-211897","R-HSA-211945","R-HSA-211976","R-HSA-2168880","R-HSA-2173782","R-HSA-2187338","R-HSA-2262752","R-HSA-3000471","R-HSA-3000480","R-HSA-3000484","R-HSA-3000497","R-HSA-382551","R-HSA-382556","R-HSA-418346","R-HSA-432142","R-HSA-5358346","R-HSA-5358351","R-HSA-5362768","R-HSA-5387390","R-HSA-556833","R-HSA-5619084","R-HSA-5619115","R-HSA-5653656","R-HSA-5663202","R-HSA-5679090","R-HSA-5679096","R-HSA-5682113","R-HSA-5686938","R-HSA-6805567","R-HSA-6806667","R-HSA-6807047","R-HSA-6807062","R-HSA-6809371","R-HSA-8856825","R-HSA-8856828","R-HSA-8866423","R-HSA-8935690","R-HSA-8953897","R-HSA-8957322","R-HSA-8963676","R-HSA-8963678","R-HSA-8963743","R-HSA-8963888","R-HSA-8963896","R-HSA-8963898","R-HSA-8963899","R-HSA-8963901","R-HSA-8964011","R-HSA-8964026","R-HSA-8964038","R-HSA-8964041","R-HSA-8964043","R-HSA-8964046","R-HSA-8964058","R-HSA-8979227","R-HSA-9707616","R-HSA-9709957","R-HSA-975634"],"reactome_names":["Hemostasis","Developmental Biology","ABC transporters in lipid homeostasis","Metabolism","Phase II - Conjugation of compounds","Cytosolic sulfonation of small molecules","Signal Transduction","Triglyceride catabolism","Disease","Regulation of cholesterol biosynthesis by SREBP (SREBF)","Innate Immune System","Immune System","Toll-like Receptor Cascades","Plasma lipoprotein assembly, remodeling, and clearance","Cholesterol biosynthesis","Synthesis of bile acids and bile salts","Digestion of dietary lipid","Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol","Synthesis of bile acids and bile salts via 24-hydroxycholesterol","Synthesis of bile acids and bile salts via 27-hydroxycholesterol","Bile acid and bile salt metabolism","Metabolism of steroid hormones","Pregnenolone biosynthesis","Metabolism of vitamins and cofactors","Membrane Trafficking","Cell surface interactions at the vascular wall","Biological oxidations","Cytochrome P450 - arranged by substrate type","Phase I - Functionalization of compounds","Endogenous sterols","Scavenging of heme from plasma","Binding and Uptake of Ligands by Scavenger Receptors","Visual phototransduction","Cellular responses to stress","Scavenging by Class B Receptors","Scavenging by Class A Receptors","Scavenging by Class F Receptors","Scavenging by Class H Receptors","Transport of small molecules","ABC-family proteins mediated transport","Platelet homeostasis","Platelet sensitization by LDL","Hedgehog ligand biogenesis","Signaling by Hedgehog","Hh mutants are degraded by ERAD","Hh mutants abrogate ligand secretion","Metabolism of lipids","ABC transporter disorders","Disorders of transmembrane transporters","Vesicle-mediated transport","Diseases of signal transduction by growth factor receptors and second messengers","Defective ABCG8 causes GBD4 and sitosterolemia","Defective ABCG5 causes sitosterolemia","Defective ABCA1 causes TGD","Regulation of TLR by endogenous ligand","Keratinization","Metabolism of fat-soluble vitamins","Cholesterol biosynthesis via desmosterol","Cholesterol biosynthesis via lathosterol","Formation of the cornified envelope","Cargo recognition for clathrin-mediated endocytosis","Clathrin-mediated endocytosis","VLDL assembly","Digestion","Cellular responses to stimuli","Metabolism of steroids","Intestinal absorption","Intestinal lipid absorption","Digestion and absorption","Chylomicron assembly","HDL assembly","Plasma lipoprotein assembly","Plasma lipoprotein remodeling","Chylomicron remodeling","HDL clearance","Chylomicron clearance","LDL clearance","LDL remodeling","Plasma lipoprotein clearance","VLDL clearance","HDL remodeling","Triglyceride metabolism","Heme signaling","Sensory Perception","Retinoid metabolism and transport"],"study_id_observed":["MTBLS106","MTBLS1196","MTBLS159","MTBLS1830","MTBLS1980","MTBLS208","MTBLS2145","MTBLS2279","MTBLS2322","MTBLS2324","MTBLS2406","MTBLS2457","MTBLS312","MTBLS3750","MTBLS3963","MTBLS40","MTBLS4013","MTBLS4099","MTBLS437","MTBLS45","MTBLS4579","MTBLS4893","MTBLS4894","MTBLS4932","MTBLS522","MTBLS533","MTBLS545","MTBLS5877","MTBLS5971","MTBLS600","MTBLS686","MTBLS6886","MTBLS726","MTBLS739","MTBLS7584","MTBLS789","MTBLS795"],"study_id_var_observed":["MTBLS1830","MTBLS1980","MTBLS2145","MTBLS2322","MTBLS2324","MTBLS4013","MTBLS437","MTBLS739"],"synonym_name":"CHOLESTEROL"}