{"chebi_id":"68647","chebi_name":"regorafenib","chebi_synonyms":["regorafenibum","r\u00e9goraf\u00e9nib","BAY 73-4506","Regorafenibum","4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]-N-methylpyridine-2-carboxamide"],"diffprof_id_observed":["MTBLS2871_0001_00000009"],"diffprof_id_var_observed":["MTBLS2871_0001_00000009"],"inchikey":"FNHKPVJBJVTLMP-UHFFFAOYSA-N","inn_name":"regorafenib","iupac_name":"4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]-<em>N</em>-methylpyridine-2-carboxamide","num_study_observed":1,"reactome_ids":["R-HSA-1433557","R-HSA-162582","R-HSA-1643685","R-HSA-186797","R-HSA-5663202","R-HSA-6802948","R-HSA-6802957","R-HSA-9006934","R-HSA-9669921","R-HSA-9669929","R-HSA-9669937","R-HSA-9669938","R-HSA-9671555","R-HSA-9674403","R-HSA-9674415","R-HSA-9674428"],"reactome_names":["Signaling by SCF-KIT","Signal Transduction","Disease","Signaling by PDGF","Diseases of signal transduction by growth factor receptors and second messengers","Signaling by high-kinase activity BRAF mutants","Oncogenic MAPK signaling","Signaling by Receptor Tyrosine Kinases","KIT mutants bind TKIs","Regorafenib-resistant KIT mutants","Drug resistance of KIT mutants","Signaling by KIT in disease","Signaling by PDGFR in disease","Regorafenib-resistant PDGFR mutants","Drug resistance of PDGFR mutants","PDGFR mutants bind TKIs"],"study_id_observed":["MTBLS2871"],"study_id_var_observed":["MTBLS2871"],"synonym_name":"BAY 73-4506"}
