{"chebi_id":"17368","chebi_name":"hypoxanthine","chebi_synonyms":["Hyp","Hypoxanthine","Purine-6-ol","6(1H)-purinone","purin-6(1H)-one","1,7-dihydro-6H-purin-6-one","HYPOXANTHINE","9H-purin-6(1H)-one","6-oxopurine"],"diffprof_id_observed":["MTBLS106_0001_00000001","MTBLS1182_0001_00000001","MTBLS1191_0001_00000001","MTBLS1191_0002_00000001","MTBLS125_0001_00000005","MTBLS125_0002_00000005","MTBLS1274_0001_00000001","MTBLS127_0001_00000027","MTBLS127_0002_00000027","MTBLS127_0003_00000002","MTBLS127_0004_00000002","MTBLS127_0005_00000002","MTBLS127_0005_00000027","MTBLS1390_0001_00000004","MTBLS1390_0002_00000004","MTBLS1411_0002_00000001","MTBLS1612_0001_00000001","MTBLS1698_0002_00000001","MTBLS1708_0001_00000006","MTBLS1792_0001_00000018","MTBLS181_0001_00000002","MTBLS1866_0001_00000001","MTBLS2015_0001_00000001","MTBLS2015_0002_00000001","MTBLS2108_0002_00000001","MTBLS2145_0001_00000029","MTBLS2145_0002_00000029","MTBLS2145_0003_00000029","MTBLS2145_0006_00000029","MTBLS2262_0002_00000008","MTBLS2279_0001_00000005","MTBLS2322_0002_00000001","MTBLS2323_0001_00000001","MTBLS23_0001_00000001","MTBLS2406_0002_00000009","MTBLS2559_0001_00000001","MTBLS2771_0001_00000002","MTBLS2887_0002_00000003","MTBLS2945_0002_00000003","MTBLS3003_0002_00000001","MTBLS3056_0001_00000001","MTBLS312_0002_00000009","MTBLS3233_0002_00000003","MTBLS3306_0001_00000014","MTBLS3306_0002_00000014","MTBLS353_0001_00000001","MTBLS3540_0001_00000002","MTBLS3627_0001_00000007","MTBLS3628_0001_00000004","MTBLS3637_0001_00000001","MTBLS3657_0001_00000003","MTBLS3750_0002_00000006","MTBLS376_0001_00000001","MTBLS376_0003_00000001","MTBLS3927_0001_00000001","MTBLS3927_0002_00000001","MTBLS3963_0002_00000001","MTBLS4046_0002_00000014","MTBLS4099_0001_00000001","MTBLS4186_0001_00000001","MTBLS4249_0002_00000001","MTBLS4463_0001_00000001","MTBLS4507_0002_00000003","MTBLS4722_0001_00000001","MTBLS4820_0002_00000001","MTBLS4893_0001_00000003","MTBLS4893_0003_00000003","MTBLS4894_0001_00000003","MTBLS4932_0001_00000005","MTBLS4967_0001_00000003","MTBLS4980_0002_00000006","MTBLS5132_0002_00000014","MTBLS5148_0002_00000014","MTBLS522_0001_00000002","MTBLS5297_0001_00000005","MTBLS5297_0002_00000005","MTBLS5335_0001_00000003","MTBLS5335_0003_00000003","MTBLS533_0001_00000001","MTBLS545_0001_00000001","MTBLS545_0002_00000001","MTBLS545_0003_00000001","MTBLS5462_0001_00000002","MTBLS5462_0001_00000050","MTBLS5462_0001_00000089","MTBLS5462_0001_00000119","MTBLS5462_0001_00000140","MTBLS5462_0001_00000152","MTBLS549_0001_00000006","MTBLS5828_0001_00000001","MTBLS5828_0002_00000001","MTBLS5877_0001_00000002","MTBLS5971_0001_00000001","MTBLS629_0002_00000001","MTBLS6337_0001_00000002","MTBLS633_0001_00000001","MTBLS6402_0002_00000001","MTBLS6516_0002_00000002","MTBLS6603_0001_00000001","MTBLS6603_0002_00000001","MTBLS6661_0002_00000001","MTBLS6758_0001_00000002","MTBLS686_0001_00000001","MTBLS6886_0001_00000001","MTBLS6890_0001_00000001","MTBLS6927_0002_00000001","MTBLS745_0001_00000002","MTBLS7584_0001_00000003","MTBLS7584_0002_00000003","MTBLS7711_0001_00000003","MTBLS7713_0001_00000003","MTBLS789_0001_00000001","MTBLS795_0001_00000001","MTBLS858_0001_00000001","MTBLS87_0001_00000001","MTBLS87_0002_00000001","MTBLS87_0004_00000001","MTBLS882_0001_00000001","MTBLS882_0002_00000001","MTBLS88_0001_00000001","MTBLS88_0003_00000001"],"diffprof_id_var_observed":["MTBLS1390_0001_00000004","MTBLS1390_0002_00000004","MTBLS1708_0001_00000006","MTBLS1792_0001_00000018","MTBLS1866_0001_00000001","MTBLS2145_0001_00000029","MTBLS2145_0002_00000029","MTBLS2145_0006_00000029","MTBLS2323_0001_00000001","MTBLS23_0001_00000001","MTBLS3056_0001_00000001","MTBLS312_0002_00000009","MTBLS3306_0001_00000014","MTBLS353_0001_00000001","MTBLS3750_0002_00000006","MTBLS376_0001_00000001","MTBLS376_0003_00000001","MTBLS4046_0002_00000014","MTBLS4099_0001_00000001","MTBLS4249_0002_00000001","MTBLS4507_0002_00000003","MTBLS4893_0001_00000003","MTBLS4893_0003_00000003","MTBLS4932_0001_00000005","MTBLS5132_0002_00000014","MTBLS5335_0001_00000003","MTBLS5335_0003_00000003","MTBLS5828_0001_00000001","MTBLS5828_0002_00000001","MTBLS5971_0001_00000001","MTBLS629_0002_00000001","MTBLS633_0001_00000001","MTBLS6661_0002_00000001","MTBLS882_0001_00000001","MTBLS882_0002_00000001"],"inchikey":"FDGQSTZJBFJUBT-UHFFFAOYSA-N","inn_name":"","iupac_name":"1,7-dihydro-6<em>H</em>-purin-6-one","num_study_observed":89,"reactome_ids":["R-HSA-110331","R-HSA-1430728","R-HSA-15869","R-HSA-1643685","R-HSA-382551","R-HSA-425397","R-HSA-425407","R-HSA-5668914","R-HSA-73884","R-HSA-73894","R-HSA-73927","R-HSA-73929","R-HSA-74217","R-HSA-74259","R-HSA-83936","R-HSA-8956319","R-HSA-8956321","R-HSA-9734207","R-HSA-9734281","R-HSA-9735804"],"reactome_names":["Cleavage of the damaged purine","Metabolism","Metabolism of nucleotides","Disease","Transport of small molecules","Transport of vitamins, nucleosides, and related molecules","SLC-mediated transmembrane transport","Diseases of metabolism","Base Excision Repair","DNA Repair","Depurination","Base-Excision Repair, AP Site Formation","Purine salvage","Purine catabolism","Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane","Nucleotide catabolism","Nucleotide salvage","Nucleotide salvage defects","Defective HPRT1 disrupts guanine and hypoxanthine salvage","Diseases of nucleotide metabolism"],"study_id_observed":["MTBLS106","MTBLS1182","MTBLS1191","MTBLS125","MTBLS127","MTBLS1274","MTBLS1390","MTBLS1411","MTBLS1612","MTBLS1698","MTBLS1708","MTBLS1792","MTBLS181","MTBLS1866","MTBLS2015","MTBLS2108","MTBLS2145","MTBLS2262","MTBLS2279","MTBLS23","MTBLS2322","MTBLS2323","MTBLS2406","MTBLS2559","MTBLS2771","MTBLS2887","MTBLS2945","MTBLS3003","MTBLS3056","MTBLS312","MTBLS3233","MTBLS3306","MTBLS353","MTBLS3540","MTBLS3627","MTBLS3628","MTBLS3637","MTBLS3657","MTBLS3750","MTBLS376","MTBLS3927","MTBLS3963","MTBLS4046","MTBLS4099","MTBLS4186","MTBLS4249","MTBLS4463","MTBLS4507","MTBLS4722","MTBLS4820","MTBLS4893","MTBLS4894","MTBLS4932","MTBLS4967","MTBLS4980","MTBLS5132","MTBLS5148","MTBLS522","MTBLS5297","MTBLS533","MTBLS5335","MTBLS545","MTBLS5462","MTBLS549","MTBLS5828","MTBLS5877","MTBLS5971","MTBLS629","MTBLS633","MTBLS6337","MTBLS6402","MTBLS6516","MTBLS6603","MTBLS6661","MTBLS6758","MTBLS686","MTBLS6886","MTBLS6890","MTBLS6927","MTBLS745","MTBLS7584","MTBLS7711","MTBLS7713","MTBLS789","MTBLS795","MTBLS858","MTBLS87","MTBLS88","MTBLS882"],"study_id_var_observed":["MTBLS1390","MTBLS1708","MTBLS1792","MTBLS1866","MTBLS2145","MTBLS23","MTBLS2323","MTBLS3056","MTBLS312","MTBLS3306","MTBLS353","MTBLS3750","MTBLS376","MTBLS4046","MTBLS4099","MTBLS4249","MTBLS4507","MTBLS4893","MTBLS4932","MTBLS5132","MTBLS5335","MTBLS5828","MTBLS5971","MTBLS629","MTBLS633","MTBLS6661","MTBLS882"],"synonym_name":"Purine-6-ol"}