{"chebi_id":"16526","chebi_name":"carbon dioxide","chebi_synonyms":["E290","E 290","R-744","E-290","methanedione","CARBON DIOXIDE","CO2","carbonic anhydride","[CO2]","dioxidocarbon","Carbon dioxide"],"diffprof_id_observed":["MTBLS2384_0002_00000005"],"diffprof_id_var_observed":[],"inchikey":"CURLTUGMZLYLDI-UHFFFAOYSA-N","inn_name":"","iupac_name":"methanedione","num_study_observed":1,"reactome_ids":["R-HSA-112122","R-HSA-112126","R-HSA-112310","R-HSA-112315","R-HSA-112316","R-HSA-1222556","R-HSA-1234174","R-HSA-1234176","R-HSA-1237044","R-HSA-1247673","R-HSA-1266738","R-HSA-1428517","R-HSA-1430728","R-HSA-1474244","R-HSA-1474290","R-HSA-1475029","R-HSA-1480926","R-HSA-1483206","R-HSA-1483213","R-HSA-1483257","R-HSA-156580","R-HSA-156588","R-HSA-15869","R-HSA-159740","R-HSA-159854","R-HSA-1614558","R-HSA-1614635","R-HSA-162582","R-HSA-1630316","R-HSA-163841","R-HSA-1640170","R-HSA-1643685","R-HSA-1650814","R-HSA-1660661","R-HSA-168249","R-HSA-168256","R-HSA-173599","R-HSA-189445","R-HSA-189451","R-HSA-191273","R-HSA-194315","R-HSA-195258","R-HSA-196757","R-HSA-196783","R-HSA-196807","R-HSA-196849","R-HSA-196854","R-HSA-1971475","R-HSA-199220","R-HSA-2022377","R-HSA-2046104","R-HSA-2046105","R-HSA-2046106","R-HSA-209776","R-HSA-209905","R-HSA-209931","R-HSA-211859","R-HSA-212165","R-HSA-2142789","R-HSA-2262752","R-HSA-2299718","R-HSA-2980736","R-HSA-3214842","R-HSA-3247509","R-HSA-351143","R-HSA-351202","R-HSA-382551","R-HSA-389542","R-HSA-389599","R-HSA-389661","R-HSA-390247","R-HSA-390918","R-HSA-392499","R-HSA-428157","R-HSA-446193","R-HSA-446199","R-HSA-446203","R-HSA-446219","R-HSA-4839726","R-HSA-500753","R-HSA-5221030","R-HSA-556833","R-HSA-5625740","R-HSA-5625886","R-HSA-5661270","R-HSA-5662702","R-HSA-597592","R-HSA-6782315","R-HSA-6782861","R-HSA-6783984","R-HSA-6787450","R-HSA-6807062","R-HSA-68875","R-HSA-68886","R-HSA-69278","R-HSA-70263","R-HSA-70268","R-HSA-70326","R-HSA-70895","R-HSA-70921","R-HSA-71032","R-HSA-71064","R-HSA-71240","R-HSA-71262","R-HSA-71291","R-HSA-71336","R-HSA-71387","R-HSA-71403","R-HSA-72306","R-HSA-73621","R-HSA-73817","R-HSA-73894","R-HSA-73942","R-HSA-73943","R-HSA-74160","R-HSA-75105","R-HSA-75876","R-HSA-77289","R-HSA-888568","R-HSA-888590","R-HSA-8953854","R-HSA-8953897","R-HSA-8956319","R-HSA-8956320","R-HSA-8957322","R-HSA-8963684","R-HSA-8963691","R-HSA-8963693","R-HSA-8978868","R-HSA-8978934","R-HSA-9629569","R-HSA-9651496","R-HSA-9668250","R-HSA-9671793","R-HSA-9673240","R-HSA-9716542","R-HSA-9816359","R-HSA-9821002","R-HSA-9853506","R-HSA-9858328","R-HSA-9859138","R-HSA-9861559"],"reactome_names":["ALKBH2 mediated reversal of alkylation damage","ALKBH3 mediated reversal of alkylation damage","Neurotransmitter release cycle","Transmission across Chemical Synapses","Neuronal System","ROS and RNS production in phagocytes","Cellular response to hypoxia","Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha","Erythrocytes take up carbon dioxide and release oxygen","Erythrocytes take up oxygen and release carbon dioxide","Developmental Biology","Aerobic respiration and respiratory electron transport","Metabolism","Extracellular matrix organization","Collagen formation","Reversible hydration of carbon dioxide","O2/CO2 exchange in erythrocytes","Glycerophospholipid biosynthesis","Synthesis of PE","Phospholipid metabolism","Phase II - Conjugation of compounds","Glucuronidation","Metabolism of nucleotides","Gamma-carboxylation of protein precursors","Gamma-carboxylation, transport, and amino-terminal cleavage of proteins","Degradation of cysteine and homocysteine","Sulfur amino acid metabolism","Signal Transduction","Glycosaminoglycan metabolism","Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation","Cell Cycle","Disease","Collagen biosynthesis and modifying enzymes","Sphingolipid de novo biosynthesis","Innate Immune System","Immune System","Formation of the active cofactor, UDP-glucuronate","Metabolism of porphyrins","Heme biosynthesis","Cholesterol biosynthesis","Signaling by Rho GTPases","RHO GTPase Effectors","Metabolism of folate and pterines","Coenzyme A biosynthesis","Nicotinate metabolism","Metabolism of water-soluble vitamins and cofactors","Metabolism of vitamins and cofactors","Glycosaminoglycan-protein linkage region biosynthesis","Vitamin B5 (pantothenate) metabolism","Metabolism of Angiotensinogen to Angiotensins","alpha-linolenic (omega3) and linoleic (omega6) acid metabolism","Linoleic acid (LA) metabolism","alpha-linolenic acid (ALA) metabolism","Metabolism of amine-derived hormones","Catecholamine biosynthesis","Serotonin and melatonin biosynthesis","Biological oxidations","Epigenetic regulation of gene expression","Ubiquinol biosynthesis","Cellular responses to stress","Condensation of Prophase Chromosomes","Peptide hormone metabolism","HDMs demethylate histones","Chromatin modifying enzymes","Agmatine biosynthesis","Metabolism of polyamines","Transport of small molecules","NADPH regeneration","Alpha-oxidation of phytanate","Glyoxylate metabolism and glycine degradation","Beta-oxidation of very long chain fatty acids","Peroxisomal lipid metabolism","Metabolism of proteins","Sphingolipid metabolism","Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein","Synthesis of dolichyl-phosphate","Asparagine N-linked glycosylation","Synthesis of substrates in N-glycan biosythesis","Chromatin organization","Pyrimidine biosynthesis","TET1,2,3 and TDG demethylate DNA","Metabolism of lipids","RHO GTPases activate PKNs","Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3","Formation of xylulose-5-phosphate","Melanin biosynthesis","Post-translational protein modification","tRNA modification in the nucleus and cytosol","Synthesis of wybutosine at G37 of tRNA(Phe)","Glycine degradation","tRNA modification in the mitochondrion","Cholesterol biosynthesis via lathosterol","Mitotic Prophase","M Phase","Cell Cycle, Mitotic","Gluconeogenesis","Pyruvate metabolism","Glucose metabolism","Branched-chain amino acid catabolism","Histidine catabolism","Propionyl-CoA catabolism","Lysine catabolism","Tryptophan catabolism","Carnitine synthesis","Metabolism of amino acids and derivatives","Pentose phosphate pathway","Metabolism of carbohydrates and carbohydrate derivatives","Citric acid cycle (TCA cycle)","tRNA processing","Pyrimidine catabolism","Purine ribonucleoside monophosphate biosynthesis","DNA Repair","DNA Damage Reversal","Reversal of alkylation damage by DNA dioxygenases","Gene expression (Transcription)","Fatty acyl-CoA biosynthesis","Synthesis of very long-chain fatty acyl-CoAs","Mitochondrial Fatty Acid Beta-Oxidation","GABA synthesis","GABA synthesis, release, reuptake and degradation","Metabolism of RNA","Cellular responses to stimuli","Nucleotide catabolism","Nucleotide biosynthesis","Metabolism of steroids","Tyrosine catabolism","Phenylalanine and tyrosine metabolism","Aspartate and asparagine metabolism","Fatty acid metabolism","Metabolism of cofactors","Protein hydroxylation","Defects of contact activation system (CAS) and kallikrein/kinin system (KKS)","Defective factor IX causes hemophilia B","Diseases of hemostasis","Defective gamma-carboxylation of F9","Signaling by Rho GTPases, Miro GTPases and RHOBTB3","Maternal to zygotic transition (MZT)","Chromatin modifications during the maternal to zygotic transition (MZT)","OGDH complex synthesizes succinyl-CoA from 2-OG","OADH complex synthesizes glutaryl-CoA from 2-OA","BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV","PDH complex synthesizes acetyl-CoA from PYR"],"study_id_observed":["MTBLS2384"],"study_id_var_observed":[],"synonym_name":"R-744"}