{"chebi_id":"63452","chebi_name":"midostaurin","chebi_synonyms":["CGP 41251","CGP-41251","4'-N-benzoylstaurosporine","PKC 412","PKC412","N-[(5S,6R,7R,9R)-6-methoxy-5-methyl-14-oxo-6,7,8,9,15,16-hexahydro-5H,14H-5,9-epoxy-4b,9a,15-triazadibenzo[b,h]cyclonona[1,2,3,4-jkl]cyclopenta[e]-as-indacen-7-yl]-N-methylbenzamide","benzoylstaurosporine"],"diffprof_id_observed":["MTBLS3750_0001_00000006"],"diffprof_id_var_observed":["MTBLS3750_0001_00000006"],"inchikey":"BMGQWWVMWDBQGC-IIFHNQTCSA-N","inn_name":"midostaurin","iupac_name":"<em>N</em>-[(5<i>S</i>,6<i>R</i>,7<i>R</i>,9<i>R</i>)-6-methoxy-5-methyl-14-oxo-6,7,8,9,15,16-hexahydro-5<em>H</em>,14<em>H</em>-5,9-epoxy-4b,9a,15-triazadibenzo[<em>b</em>,<em>h</em>]cyclonona[1,2,3,4-<em>jkl</em>]cyclopenta[e]-<em>as</em>-indacen-7-yl]-<em>N</em>-methylbenzamide","num_study_observed":1,"reactome_ids":["R-HSA-1226099","R-HSA-1280215","R-HSA-1433557","R-HSA-162582","R-HSA-1643685","R-HSA-168256","R-HSA-1839117","R-HSA-1839124","R-HSA-5655302","R-HSA-5655332","R-HSA-5663202","R-HSA-9006934","R-HSA-9607240","R-HSA-9669921","R-HSA-9669938","R-HSA-9682385","R-HSA-9702506","R-HSA-9702509","R-HSA-9702600"],"reactome_names":["Signaling by FGFR in disease","Cytokine Signaling in Immune system","Signaling by SCF-KIT","Signal Transduction","Disease","Immune System","Signaling by cytosolic FGFR1 fusion mutants","FGFR1 mutant receptor activation","Signaling by FGFR1 in disease","Signaling by FGFR3 in disease","Diseases of signal transduction by growth factor receptors and second messengers","Signaling by Receptor Tyrosine Kinases","FLT3 Signaling","KIT mutants bind TKIs","Signaling by KIT in disease","FLT3 signaling in disease","Drug resistance of FLT3 mutants","FLT3 mutants bind TKIs","midostaurin-resistant FLT3 mutants"],"study_id_observed":["MTBLS3750"],"study_id_var_observed":["MTBLS3750"],"synonym_name":"CGP 41251"}