{"chebi_id":"58045","chebi_name":"L-isoleucine zwitterion","chebi_synonyms":["(2S,3S)-2-ammonio-3-methylpentanoate","L-isoleucine","(2S,3S)-2-azaniumyl-3-methylpentanoate"],"diffprof_id_observed":["MTBLS106_0001_00000001","MTBLS140_0002_00000008","MTBLS140_0003_00000008","MTBLS1443_0002_00000001","MTBLS159_0001_00000001","MTBLS159_0002_00000001","MTBLS159_0003_00000001","MTBLS159_0004_00000001","MTBLS1612_0001_00000001","MTBLS1796_0001_00000001","MTBLS181_0001_00000002","MTBLS1830_0001_00000001","MTBLS1858_0001_00000001","MTBLS1866_0001_00000001","MTBLS1980_0001_00000001","MTBLS2014_0001_00000001","MTBLS2015_0001_00000001","MTBLS2015_0002_00000001","MTBLS208_0001_00000006","MTBLS2104_0002_00000028","MTBLS2108_0001_00000001","MTBLS2145_0001_00000029","MTBLS2145_0002_00000029","MTBLS2145_0003_00000029","MTBLS226_0001_00000024","MTBLS2279_0001_00000005","MTBLS2317_0002_00000001","MTBLS2322_0001_00000001","MTBLS2322_0002_00000001","MTBLS2323_0001_00000001","MTBLS2323_0002_00000001","MTBLS2324_0001_00000001","MTBLS2324_0002_00000001","MTBLS2597_0001_00000001","MTBLS2721_0003_00000007","MTBLS2771_0001_00000002","MTBLS280_0003_00000001","MTBLS280_0004_00000001","MTBLS280_0006_00000001","MTBLS2840_0002_00000026","MTBLS2870_0001_00000277","MTBLS293_0002_00000005","MTBLS295_0002_00000001","MTBLS297_0001_00000001","MTBLS3003_0002_00000001","MTBLS3038_0002_00000001","MTBLS3056_0002_00000001","MTBLS30_0001_00000002","MTBLS312_0002_00000009","MTBLS3306_0002_00000014","MTBLS3318_0001_00000001","MTBLS3358_0001_00000001","MTBLS3518_0001_00000001","MTBLS353_0001_00000001","MTBLS3540_0001_00000002","MTBLS3628_0001_00000004","MTBLS3657_0001_00000003","MTBLS3725_0002_00000003","MTBLS376_0001_00000001","MTBLS376_0003_00000001","MTBLS3854_0002_00000001","MTBLS3886_0002_00000004","MTBLS3950_0001_00000001","MTBLS403_0001_00000008","MTBLS4099_0001_00000001","MTBLS40_0001_00000001","MTBLS4249_0002_00000001","MTBLS4365_0001_00000002","MTBLS43_0001_00000003","MTBLS4469_0001_00000001","MTBLS44_0001_00000003","MTBLS4542_0001_00000001","MTBLS4579_0001_00000001","MTBLS4722_0001_00000001","MTBLS4820_0002_00000001","MTBLS4893_0001_00000003","MTBLS4893_0002_00000003","MTBLS4894_0001_00000003","MTBLS4932_0001_00000005","MTBLS4980_0002_00000006","MTBLS522_0001_00000002","MTBLS5297_0001_00000005","MTBLS533_0001_00000001","MTBLS545_0001_00000001","MTBLS545_0002_00000001","MTBLS545_0003_00000001","MTBLS5462_0001_00000002","MTBLS5462_0001_00000050","MTBLS5462_0001_00000089","MTBLS5462_0001_00000119","MTBLS5462_0001_00000140","MTBLS5462_0001_00000152","MTBLS549_0001_00000006","MTBLS54_0001_00000003","MTBLS5943_0001_00000001","MTBLS5971_0001_00000001","MTBLS627_0001_00000001","MTBLS633_0001_00000001","MTBLS6516_0002_00000002","MTBLS656_0001_00000031","MTBLS6663_0001_00000006","MTBLS686_0001_00000001","MTBLS6890_0002_00000001","MTBLS6927_0002_00000001","MTBLS726_0001_00000001","MTBLS7584_0001_00000003","MTBLS7584_0003_00000003","MTBLS779_0001_00000001","MTBLS789_0001_00000001","MTBLS795_0001_00000001","MTBLS809_0001_00000001","MTBLS87_0001_00000001","MTBLS87_0002_00000001","MTBLS87_0004_00000001","MTBLS883_0001_00000014","MTBLS88_0001_00000001","MTBLS88_0003_00000001","MTBLS893_0001_00000001"],"diffprof_id_var_observed":["MTBLS1830_0001_00000001","MTBLS1858_0001_00000001","MTBLS2145_0001_00000029","MTBLS2145_0002_00000029","MTBLS2322_0001_00000001","MTBLS2322_0002_00000001","MTBLS2323_0001_00000001","MTBLS2323_0002_00000001","MTBLS2324_0001_00000001","MTBLS2597_0001_00000001","MTBLS2840_0002_00000026","MTBLS2870_0001_00000277","MTBLS297_0001_00000001","MTBLS3038_0002_00000001","MTBLS312_0002_00000009","MTBLS376_0001_00000001","MTBLS376_0003_00000001","MTBLS3886_0002_00000004","MTBLS3950_0001_00000001","MTBLS403_0001_00000008","MTBLS4099_0001_00000001","MTBLS4542_0001_00000001","MTBLS4893_0001_00000003","MTBLS4894_0001_00000003","MTBLS4932_0001_00000005","MTBLS4980_0002_00000006","MTBLS522_0001_00000002","MTBLS5462_0001_00000002","MTBLS549_0001_00000006","MTBLS633_0001_00000001","MTBLS779_0001_00000001","MTBLS809_0001_00000001"],"inchikey":"AGPKZVBTJJNPAG-WHFBIAKZSA-N","inn_name":"","iupac_name":"(2<i>S</i>,3<i>S</i>)-2-azaniumyl-3-methylpentanoate","num_study_observed":93,"reactome_ids":["R-HSA-1430728","R-HSA-1643685","R-HSA-352230","R-HSA-379716","R-HSA-379724","R-HSA-379726","R-HSA-382551","R-HSA-392499","R-HSA-425407","R-HSA-442660","R-HSA-5619044","R-HSA-5619094","R-HSA-5619102","R-HSA-5619115","R-HSA-5659735","R-HSA-70895","R-HSA-71240","R-HSA-71291","R-HSA-72766","R-HSA-9958863"],"reactome_names":["Metabolism","Disease","Amino acid transport across the plasma membrane","Cytosolic tRNA aminoacylation","tRNA Aminoacylation","Mitochondrial tRNA aminoacylation","Transport of small molecules","Metabolism of proteins","SLC-mediated transmembrane transport","SLC-mediated transport of neurotransmitters","Defective SLC6A19 causes Hartnup disorder (HND)","Variant SLC6A14 may confer susceptibility towards obesity","SLC transporter disorders","Disorders of transmembrane transporters","Defective SLC6A19 causes Hartnup disorder (HND)","Branched-chain amino acid catabolism","Tryptophan catabolism","Metabolism of amino acids and derivatives","Translation","SLC-mediated transport of amino acids"],"study_id_observed":["MTBLS106","MTBLS140","MTBLS1443","MTBLS159","MTBLS1612","MTBLS1796","MTBLS181","MTBLS1830","MTBLS1858","MTBLS1866","MTBLS1980","MTBLS2014","MTBLS2015","MTBLS208","MTBLS2104","MTBLS2108","MTBLS2145","MTBLS226","MTBLS2279","MTBLS2317","MTBLS2322","MTBLS2323","MTBLS2324","MTBLS2597","MTBLS2721","MTBLS2771","MTBLS280","MTBLS2840","MTBLS2870","MTBLS293","MTBLS295","MTBLS297","MTBLS30","MTBLS3003","MTBLS3038","MTBLS3056","MTBLS312","MTBLS3306","MTBLS3318","MTBLS3358","MTBLS3518","MTBLS353","MTBLS3540","MTBLS3628","MTBLS3657","MTBLS3725","MTBLS376","MTBLS3854","MTBLS3886","MTBLS3950","MTBLS40","MTBLS403","MTBLS4099","MTBLS4249","MTBLS43","MTBLS4365","MTBLS44","MTBLS4469","MTBLS4542","MTBLS4579","MTBLS4722","MTBLS4820","MTBLS4893","MTBLS4894","MTBLS4932","MTBLS4980","MTBLS522","MTBLS5297","MTBLS533","MTBLS54","MTBLS545","MTBLS5462","MTBLS549","MTBLS5943","MTBLS5971","MTBLS627","MTBLS633","MTBLS6516","MTBLS656","MTBLS6663","MTBLS686","MTBLS6890","MTBLS6927","MTBLS726","MTBLS7584","MTBLS779","MTBLS789","MTBLS795","MTBLS809","MTBLS87","MTBLS88","MTBLS883","MTBLS893"],"study_id_var_observed":["MTBLS1830","MTBLS1858","MTBLS2145","MTBLS2322","MTBLS2323","MTBLS2324","MTBLS2597","MTBLS2840","MTBLS2870","MTBLS297","MTBLS3038","MTBLS312","MTBLS376","MTBLS3886","MTBLS3950","MTBLS403","MTBLS4099","MTBLS4542","MTBLS4893","MTBLS4894","MTBLS4932","MTBLS4980","MTBLS522","MTBLS5462","MTBLS549","MTBLS633","MTBLS779","MTBLS809"],"synonym_name":"(2<i>S</i>,3<i>S</i>)-2-ammonio-3-methylpentanoate"}