{"comparisonGroups":["IDH1WT_U251_ER_Untreated","IDH1R132C_U251_ER_Untreated"],"dateCreated":"2025-09-26 00:00:00","display_title":"U251 cells: IDH1 wild-type vs IDH1R132C mutation in ER","group_a_title":"U251 cells with wild-type IDH1 in the endoplasmic reticulum, untreated.. Provides baseline data for comparison with IDH1 mutant samples.","group_b_title":"U251 cells with IDH1R132C mutation in the endoplasmic reticulum, untreated.. Helps in understanding the morphological changes in the ER due to IDH1R132C mutation.","id":"MTBLS1973_0001_00000002","pvalueThreshold":0.05,"ratioThresholdLower":"1/1.5","ratioThresholdUpper":1.5,"significantFeatures":2,"studyId":"MTBLS1973","studyUrl":"http://integmet.org/study/MTBLS1973","title":"G3_IDH1WT_U251_ER_Untreated_vs_G1_IDH1R132C_U251_ER_Untreated","topHits":[{"chebi_id":"17023","direction":"down","inn_name":"","iupac_name":"2-hydroxyhexanedioic acid","metabolite_id":"OTTXIFWBPRRYOG-UHFFFAOYSA-N","pvalue":0.0010068454395509,"ratio":0.3094551430723196,"synonym_name":"2-Hydroxyadipate"},{"chebi_id":"28364","direction":"down","inn_name":"icosapentum","iupac_name":"(5<i>Z</i>,8<i>Z</i>,11<i>Z</i>,14<i>Z</i>,17<i>Z</i>)-icosa-5,8,11,14,17-pentaenoic acid","metabolite_id":"JAZBEHYOTPTENJ-JLNKQSITSA-N","pvalue":0.0126736286475917,"ratio":0.6619401183747539,"synonym_name":"5,8,11,14,17-EICOSAPENTAENOIC ACID"}],"totalFeatures":7}